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LDN Doctor vs ProlongMD: Which Is Better?

Head-to-head comparison of LDN Doctor and ProlongMD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

LDN Doctor scores higher overall in our independent evaluation (60.2/100 vs 60.1/100), leading on trust & safety, experience, reputation. ProlongMD comes out ahead on value, product range.

60

LDN Doctor is a small physician practice (H Handler MD Inc) that prescribes low-dose naltrexone by paid video consult, with the medication bought separately from a pharmacy.

Visit LDN Doctor
60

Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

Visit ProlongMD

Score Breakdown

DimensionLDN DoctorProlongMD
Overall Score60.2/100 ✓60.1/100
Trust & Safety30%60/100 ✓52/100
Value25%72/10074/100 ✓
Experience20%58/100 ✓55/100
Product Range15%45/10070/100 ✓
Reputation10%58/100 ✓45/100

At a Glance

Founded—2025
Headquarters—Phoenix, AZ
Publicly tradedNoNo
Treatment categories18
Treatments listed113
Starting price$17/mo$25/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryLDN DoctorProlongMD
Primary Care$17–$30
Low-Dose Naltrexone Consult + 6-month Rx
$79
Consultation (30-min video, credited toward treatment)

LDN Doctor

+Pay-per-visit model with published fees ($220 first visit, $130 returning) and no recurring membership
+Each consult covers a 6-month prescription, keeping the all-in cost near $35–$65/month including pharmacy
+Long-running, LDN-focused practice claiming 10,000+ patients
−All fees are non-refundable, including when the prescriber declines to prescribe LDN
−Prescribers and dispensing pharmacies are not named on the site
−LDN use for autoimmune and pain conditions is off-label, with a limited evidence base
Read the full LDN Doctor review →

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee
+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs
+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits
−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form
−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)
−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text
Read the full ProlongMD review →

LDN Doctor vs ProlongMD — FAQ

Is LDN Doctor better than ProlongMD?

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LDN Doctor scores higher overall in our independent evaluation (60.2/100 vs 60.1/100), leading on trust & safety, experience, reputation. ProlongMD comes out ahead on value, product range.

Is LDN Doctor or ProlongMD cheaper?

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LDN Doctor has the lower starting price (from $17/mo vs $25/mo for ProlongMD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do LDN Doctor and ProlongMD both offer?

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Both platforms treat Primary Care. LDN Doctor covers 1 treatment category total and ProlongMD covers 8.

Still deciding?

LDN Doctor alternativesProlongMD alternativesTake the Match Quiz