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LifeMD vs ProlongMD: Which Is Better?

Head-to-head comparison of LifeMD and ProlongMD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

LifeMD scores higher overall in our independent evaluation (68/100 vs 60.1/100), leading on trust & safety, value, experience, reputation. ProlongMD comes out ahead on product range.

68
LifeMD
Good

Publicly traded telehealth betting big on weight loss, with aggressive GLP-1 pricing and fast-growing subscriber base.

Visit LifeMD
60

Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

Visit ProlongMD

Score Breakdown

DimensionLifeMDProlongMD
Overall Score68/100 ✓60.1/100
Trust & Safety30%65/100 ✓52/100
Value25%75/100 ✓74/100
Experience20%70/100 ✓55/100
Product Range15%65/10070/100 ✓
Reputation10%60/100 ✓45/100

At a Glance

Founded20202025
HeadquartersNew York, NYPhoenix, AZ
Publicly tradedYes (LFMD)No
Treatment categories68
Treatments listed513
Starting price$14/mo$25/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryLifeMDProlongMD
Weight Loss / GLP-1$149–$349
Branded Wegovy (oral/injectable)
$99–$119
Compounded Semaglutide/B12
Men's Health—$129–$159
Enclomiphene 25 mg
Sexual Health$14–$38
Sildenafil (via Rex MD)
$75
Tadalafil 24 mg
Hair Loss$14–$27
Finasteride (via Rex MD)
$25
Oral Finasteride 5 mg
Hormone Therapy$99
Testosterone Program (via Rex MD)
$89–$119
Testosterone Cypionate (200 mg/mL)

LifeMD

+Novo Nordisk partnership for branded Wegovy pill and subscription program
+Eli Lilly partnership for branded Zepbound access
+Publicly traded with quarterly earnings transparency — 25% revenue growth in 2025
−Compounded GLP-1s discontinued — pivoted to branded medications
−Aggressive marketing draws scrutiny from health professionals
−Narrower treatment range than Hims or Ro
Read the full LifeMD review →

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee
+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs
+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits
−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form
−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)
−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text
Read the full ProlongMD review →

LifeMD vs ProlongMD — FAQ

Is LifeMD better than ProlongMD?

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LifeMD scores higher overall in our independent evaluation (68/100 vs 60.1/100), leading on trust & safety, value, experience, reputation. ProlongMD comes out ahead on product range.

Is LifeMD or ProlongMD cheaper?

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LifeMD has the lower starting price (from $14/mo vs $25/mo for ProlongMD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do LifeMD and ProlongMD both offer?

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Both platforms treat Weight Loss / GLP-1, Men's Health, Sexual Health, Hair Loss, Hormone Therapy. LifeMD covers 6 treatment categories total and ProlongMD covers 8.

Still deciding?

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