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LifeMD vs RxSpan MD: Which Is Better?

Head-to-head comparison of LifeMD and RxSpan MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

LifeMD scores higher overall in our independent evaluation (68/100 vs 59.1/100), leading on trust & safety, value, experience, reputation. RxSpan MD comes out ahead on product range.

68
LifeMD
Good

Publicly traded telehealth betting big on weight loss, with aggressive GLP-1 pricing and fast-growing subscriber base.

Visit LifeMD
59

RxSpan MD is a Beverly Hills telehealth practice founded by a plastic surgeon, offering compounded and branded GLP-1s, longevity peptides, hair-loss and ED treatment.

Visit RxSpan MD

Score Breakdown

DimensionLifeMDRxSpan MD
Overall Score68/100 ✓59.1/100
Trust & Safety30%65/100 ✓60/100
Value25%75/100 ✓58/100
Experience20%70/100 ✓52/100
Product Range15%65/10078/100 ✓
Reputation10%60/100 ✓45/100

At a Glance

Founded20202026
HeadquartersNew York, NYBeverly Hills, CA
Publicly tradedYes (LFMD)No
Treatment categories64
Treatments listed59
Starting price$14/mo$30/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryLifeMDRxSpan MD
Weight Loss / GLP-1$149–$349
Branded Wegovy (oral/injectable)
$249–$299
Compounded Semaglutide (injection or oral)
Sexual Health$14–$38
Sildenafil (via Rex MD)
$30–$100
ED (tadalafil, sildenafil/pycnogenol, vardenafil)
Hair Loss$14–$27
Finasteride (via Rex MD)
$30–$80
Hair Loss (oral minoxidil, finasteride/minoxidil, dutasteride)

LifeMD

+Novo Nordisk partnership for branded Wegovy pill and subscription program
+Eli Lilly partnership for branded Zepbound access
+Publicly traded with quarterly earnings transparency — 25% revenue growth in 2025
−Compounded GLP-1s discontinued — pivoted to branded medications
−Aggressive marketing draws scrutiny from health professionals
−Narrower treatment range than Hims or Ro
Read the full LifeMD review →

RxSpan MD

+Physician-founded practice with a named founder and a stated Beverly Hills address
+Offers both compounded (injection and oral) and branded GLP-1s, including cash-pay Zepbound listed at $500
+Third-party coverage reports named 503A pharmacy partners and free expedited shipping
−Compounded prices aren't visible on the public site; its product catalog failed to load during our research
−Brand-stated first-month prices ($249 semaglutide, $329 tirzepatide) are above peer averages, and renewal pricing is not published
−Site configuration shows an $80 initial visit fee that is not prominently disclosed
Read the full RxSpan MD review →

LifeMD vs RxSpan MD — FAQ

Is LifeMD better than RxSpan MD?

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LifeMD scores higher overall in our independent evaluation (68/100 vs 59.1/100), leading on trust & safety, value, experience, reputation. RxSpan MD comes out ahead on product range.

Is LifeMD or RxSpan MD cheaper?

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LifeMD has the lower starting price (from $14/mo vs $30/mo for RxSpan MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do LifeMD and RxSpan MD both offer?

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Both platforms treat Weight Loss / GLP-1, Sexual Health, Hair Loss. LifeMD covers 6 treatment categories total and RxSpan MD covers 4.

Still deciding?

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