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MadeMed vs ProlongMD: Which Is Better?

Head-to-head comparison of MadeMed and ProlongMD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

ProlongMD scores higher overall in our independent evaluation (60.1/100 vs 57.3/100), leading on value, experience. MadeMed comes out ahead on trust & safety, product range.

57

MadeMed is a Houston-registered telehealth brand selling compounded injectable and oral GLP-1s, sermorelin, NAD+ and tadalafil through the Xpedicare provider network.

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60

Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

Visit ProlongMD

Score Breakdown

DimensionMadeMedProlongMD
Overall Score57.3/10060.1/100 ✓
Trust & Safety30%55/100 ✓52/100
Value25%66/10074/100 ✓
Experience20%45/10055/100 ✓
Product Range15%72/100 ✓70/100
Reputation10%45/10045/100

At a Glance

Founded—2025
HeadquartersHouston, TXPhoenix, AZ
Publicly tradedNoNo
Treatment categories38
Treatments listed713
Starting price$30/mo$25/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryMadeMedProlongMD
Weight Loss / GLP-1$99–$199
Compounded Semaglutide (injectable)
$99–$119
Compounded Semaglutide/B12
Longevity & Peptides$129–$229
Sermorelin (injectable or oral)
$179
Sermorelin
Sexual Health$30–$90
Tadalafil
$75
Tadalafil 24 mg

MadeMed

+Offers both injectable and oral/sublingual versions of semaglutide, tirzepatide and sermorelin, plus NAD+ as injection or nasal spray
+Operating entity, provider network (Xpedicare) and a partner pharmacy (Red Rock) are named in the terms and About page
+Advertised GLP-1 entry pricing from $99/mo is at the low end of the market
−Product pages showed no pricing or product detail during our research, in a direct fetch or a real browser
−Advertised prices and state coverage (about 40 states) come from brand-issued press releases and can't be verified on-site
−No Trustpilot or other independent patient reviews; public coverage is mostly paid newswire content
Read the full MadeMed review →

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee
+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs
+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits
−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form
−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)
−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text
Read the full ProlongMD review →

MadeMed vs ProlongMD — FAQ

Is MadeMed better than ProlongMD?

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ProlongMD scores higher overall in our independent evaluation (60.1/100 vs 57.3/100), leading on value, experience. MadeMed comes out ahead on trust & safety, product range.

Is MadeMed or ProlongMD cheaper?

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ProlongMD has the lower starting price (from $25/mo vs $30/mo for MadeMed). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do MadeMed and ProlongMD both offer?

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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides, Sexual Health. MadeMed covers 3 treatment categories total and ProlongMD covers 8.

Still deciding?

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