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MadeMed vs RxSpan MD: Which Is Better?

Head-to-head comparison of MadeMed and RxSpan MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

RxSpan MD scores higher overall in our independent evaluation (59.1/100 vs 57.3/100), leading on trust & safety, experience, product range. MadeMed comes out ahead on value.

57

MadeMed is a Houston-registered telehealth brand selling compounded injectable and oral GLP-1s, sermorelin, NAD+ and tadalafil through the Xpedicare provider network.

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59

RxSpan MD is a Beverly Hills telehealth practice founded by a plastic surgeon, offering compounded and branded GLP-1s, longevity peptides, hair-loss and ED treatment.

Visit RxSpan MD

Score Breakdown

DimensionMadeMedRxSpan MD
Overall Score57.3/10059.1/100 ✓
Trust & Safety30%55/10060/100 ✓
Value25%66/100 ✓58/100
Experience20%45/10052/100 ✓
Product Range15%72/10078/100 ✓
Reputation10%45/10045/100

At a Glance

Founded—2026
HeadquartersHouston, TXBeverly Hills, CA
Publicly tradedNoNo
Treatment categories34
Treatments listed79
Starting price$30/mo$30/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryMadeMedRxSpan MD
Weight Loss / GLP-1$99–$199
Compounded Semaglutide (injectable)
$249–$299
Compounded Semaglutide (injection or oral)
Longevity & Peptides$129–$229
Sermorelin (injectable or oral)
$100–$200
Glutathione
Sexual Health$30–$90
Tadalafil
$30–$100
ED (tadalafil, sildenafil/pycnogenol, vardenafil)

MadeMed

+Offers both injectable and oral/sublingual versions of semaglutide, tirzepatide and sermorelin, plus NAD+ as injection or nasal spray
+Operating entity, provider network (Xpedicare) and a partner pharmacy (Red Rock) are named in the terms and About page
+Advertised GLP-1 entry pricing from $99/mo is at the low end of the market
−Product pages showed no pricing or product detail during our research, in a direct fetch or a real browser
−Advertised prices and state coverage (about 40 states) come from brand-issued press releases and can't be verified on-site
−No Trustpilot or other independent patient reviews; public coverage is mostly paid newswire content
Read the full MadeMed review →

RxSpan MD

+Physician-founded practice with a named founder and a stated Beverly Hills address
+Offers both compounded (injection and oral) and branded GLP-1s, including cash-pay Zepbound listed at $500
+Third-party coverage reports named 503A pharmacy partners and free expedited shipping
−Compounded prices aren't visible on the public site; its product catalog failed to load during our research
−Brand-stated first-month prices ($249 semaglutide, $329 tirzepatide) are above peer averages, and renewal pricing is not published
−Site configuration shows an $80 initial visit fee that is not prominently disclosed
Read the full RxSpan MD review →

MadeMed vs RxSpan MD — FAQ

Is MadeMed better than RxSpan MD?

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RxSpan MD scores higher overall in our independent evaluation (59.1/100 vs 57.3/100), leading on trust & safety, experience, product range. MadeMed comes out ahead on value.

Is MadeMed or RxSpan MD cheaper?

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Their entry prices are similar — both start around $30/mo. Real cost depends on the specific treatment: compare the pricing tables on each review, since inclusions like consults, labs, and shipping differ.

What do MadeMed and RxSpan MD both offer?

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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides, Sexual Health. MadeMed covers 3 treatment categories total and RxSpan MD covers 4.

Still deciding?

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