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MangoRx vs ProlongMD: Which Is Better?

Head-to-head comparison of MangoRx and ProlongMD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

ProlongMD scores higher overall in our independent evaluation (60.1/100 vs 58/100), leading on value, product range. MangoRx comes out ahead on trust & safety, experience.

58

MangoRx is the Dallas-based men's health telehealth brand of Nasdaq-listed Mangoceuticals, selling compounded ED, hair-loss and oral semaglutide products alongside injectable and oral (Kyzatrex) testosterone.

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60

Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

Visit ProlongMD

Score Breakdown

DimensionMangoRxProlongMD
Overall Score58/10060.1/100 ✓
Trust & Safety30%55/100 ✓52/100
Value25%62/10074/100 ✓
Experience20%58/100 ✓55/100
Product Range15%66/10070/100 ✓
Reputation10%45/10045/100

At a Glance

Founded20212025
HeadquartersDallas, TXPhoenix, AZ
Publicly tradedYes (MGRX)No
Treatment categories58
Treatments listed513
Starting price$50/mo$25/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryMangoRxProlongMD
Men's Health—$129–$159
Enclomiphene 25 mg
Sexual Health$59–$75
Mango ED (sildenafil or tadalafil)
$75
Tadalafil 24 mg
Hair Loss$50–$80
Grow (compounded hair-loss formula)
$25
Oral Finasteride 5 mg
Hormone Therapy$99
Injectable TRT (testosterone cypionate)
$89–$119
Testosterone Cypionate (200 mg/mL)
Weight Loss / GLP-1$299
Slim (compounded oral semaglutide ODT)
$99–$119
Compounded Semaglutide/B12

MangoRx

+Injectable TRT program priced at $99/month with doctor visits, lab work and medication included (per February 2026 company release and current site listing)
+Offers a branded FDA-approved oral testosterone option (Kyzatrex-based 'Prime') alongside compounded injectable TRT, which few small men's-health platforms carry
+Public-company SEC disclosures make ownership, pharmacy relationships and finances unusually visible for a brand this size
−Going-concern risk: $228,688 cash on hand at June 30, 2026 against a six-month net loss of $4.7M, per its Q2 2026 10-Q
−Compounded products are filled by Epiq Scripts, a pharmacy majority-owned (52%) by the CEO, a related-party arrangement
−Very small patient base: Q2 2026 revenue of $68,757, down 59% year over year, and only 18 Trustpilot reviews
Read the full MangoRx review →

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee
+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs
+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits
−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form
−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)
−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text
Read the full ProlongMD review →

MangoRx vs ProlongMD — FAQ

Is MangoRx better than ProlongMD?

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ProlongMD scores higher overall in our independent evaluation (60.1/100 vs 58/100), leading on value, product range. MangoRx comes out ahead on trust & safety, experience.

Is MangoRx or ProlongMD cheaper?

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ProlongMD has the lower starting price (from $25/mo vs $50/mo for MangoRx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do MangoRx and ProlongMD both offer?

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Both platforms treat Men's Health, Sexual Health, Hair Loss, Hormone Therapy, Weight Loss / GLP-1. MangoRx covers 5 treatment categories total and ProlongMD covers 8.

Still deciding?