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MangoRx vs RxSpan MD: Which Is Better?

Head-to-head comparison of MangoRx and RxSpan MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

RxSpan MD scores higher overall in our independent evaluation (59.1/100 vs 58/100), leading on trust & safety, product range. MangoRx comes out ahead on value, experience.

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MangoRx is the Dallas-based men's health telehealth brand of Nasdaq-listed Mangoceuticals, selling compounded ED, hair-loss and oral semaglutide products alongside injectable and oral (Kyzatrex) testosterone.

Visit MangoRx
59

RxSpan MD is a Beverly Hills telehealth practice founded by a plastic surgeon, offering compounded and branded GLP-1s, longevity peptides, hair-loss and ED treatment.

Visit RxSpan MD

Score Breakdown

DimensionMangoRxRxSpan MD
Overall Score58/10059.1/100 ✓
Trust & Safety30%55/10060/100 ✓
Value25%62/100 ✓58/100
Experience20%58/100 ✓52/100
Product Range15%66/10078/100 ✓
Reputation10%45/10045/100

At a Glance

Founded20212026
HeadquartersDallas, TXBeverly Hills, CA
Publicly tradedYes (MGRX)No
Treatment categories54
Treatments listed59
Starting price$50/mo$30/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryMangoRxRxSpan MD
Sexual Health$59–$75
Mango ED (sildenafil or tadalafil)
$30–$100
ED (tadalafil, sildenafil/pycnogenol, vardenafil)
Hair Loss$50–$80
Grow (compounded hair-loss formula)
$30–$80
Hair Loss (oral minoxidil, finasteride/minoxidil, dutasteride)
Weight Loss / GLP-1$299
Slim (compounded oral semaglutide ODT)
$249–$299
Compounded Semaglutide (injection or oral)

MangoRx

+Injectable TRT program priced at $99/month with doctor visits, lab work and medication included (per February 2026 company release and current site listing)
+Offers a branded FDA-approved oral testosterone option (Kyzatrex-based 'Prime') alongside compounded injectable TRT, which few small men's-health platforms carry
+Public-company SEC disclosures make ownership, pharmacy relationships and finances unusually visible for a brand this size
−Going-concern risk: $228,688 cash on hand at June 30, 2026 against a six-month net loss of $4.7M, per its Q2 2026 10-Q
−Compounded products are filled by Epiq Scripts, a pharmacy majority-owned (52%) by the CEO, a related-party arrangement
−Very small patient base: Q2 2026 revenue of $68,757, down 59% year over year, and only 18 Trustpilot reviews
Read the full MangoRx review →

RxSpan MD

+Physician-founded practice with a named founder and a stated Beverly Hills address
+Offers both compounded (injection and oral) and branded GLP-1s, including cash-pay Zepbound listed at $500
+Third-party coverage reports named 503A pharmacy partners and free expedited shipping
−Compounded prices aren't visible on the public site; its product catalog failed to load during our research
−Brand-stated first-month prices ($249 semaglutide, $329 tirzepatide) are above peer averages, and renewal pricing is not published
−Site configuration shows an $80 initial visit fee that is not prominently disclosed
Read the full RxSpan MD review →

MangoRx vs RxSpan MD — FAQ

Is MangoRx better than RxSpan MD?

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RxSpan MD scores higher overall in our independent evaluation (59.1/100 vs 58/100), leading on trust & safety, product range. MangoRx comes out ahead on value, experience.

Is MangoRx or RxSpan MD cheaper?

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RxSpan MD has the lower starting price (from $30/mo vs $50/mo for MangoRx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do MangoRx and RxSpan MD both offer?

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Both platforms treat Sexual Health, Hair Loss, Weight Loss / GLP-1. MangoRx covers 5 treatment categories total and RxSpan MD covers 4.

Still deciding?