MangoRx vs Twentyeight Health: Which Is Better?
Head-to-head comparison of MangoRx and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.
Our Verdict
Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 58/100), leading on trust & safety, value, experience, product range, reputation.
MangoRx is the Dallas-based men's health telehealth brand of Nasdaq-listed Mangoceuticals, selling compounded ED, hair-loss and oral semaglutide products alongside injectable and oral (Kyzatrex) testosterone.
Visit MangoRxBrooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).
Visit Twentyeight HealthScore Breakdown
| Dimension | MangoRx | Twentyeight Health |
|---|---|---|
| Overall Score | 58/100 | 75/100 ✓ |
| Trust & Safety30% | 55/100 | 76/100 ✓ |
| Value25% | 62/100 | 80/100 ✓ |
| Experience20% | 58/100 | 72/100 ✓ |
| Product Range15% | 66/100 | 72/100 ✓ |
| Reputation10% | 45/100 | 70/100 ✓ |
At a Glance
| Founded | 2021 | 2018 |
| Headquarters | Dallas, TX | Brooklyn, NY |
| Publicly traded | Yes (MGRX) | No |
| Treatment categories | 5 | 4 |
| Treatments listed | 5 | 7 |
| Starting price | $50/mo | $15/mo |
Pricing Where They Compete
Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.
| Category | MangoRx | Twentyeight Health |
|---|---|---|
| Sexual Health | $59–$75 Mango ED (sildenafil or tadalafil) | — |
| Weight Loss / GLP-1 | $299 Slim (compounded oral semaglutide ODT) | — |
MangoRx
Twentyeight Health
MangoRx vs Twentyeight Health — FAQ
Is MangoRx better than Twentyeight Health?
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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 58/100), leading on trust & safety, value, experience, product range, reputation.
Is MangoRx or Twentyeight Health cheaper?
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Twentyeight Health has the lower starting price (from $15/mo vs $50/mo for MangoRx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.
What do MangoRx and Twentyeight Health both offer?
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Both platforms treat Sexual Health, Weight Loss / GLP-1. MangoRx covers 5 treatment categories total and Twentyeight Health covers 4.
Still deciding?