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Musely vs Twentyeight Health: Which Is Better?

Head-to-head comparison of Musely and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 67.9/100), leading on trust & safety, value, experience, reputation.

68
Musely
Good

Telederm compounding platform selling doctor-prescribed topicals for pigmentation, aging, and hair loss alongside a growing menopause/longevity line.

Visit Musely
75

Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

Visit Twentyeight Health

Score Breakdown

DimensionMuselyTwentyeight Health
Overall Score67.9/10075/100 ✓
Trust & Safety30%65/10076/100 ✓
Value25%70/10080/100 ✓
Experience20%68/10072/100 ✓
Product Range15%72/10072/100
Reputation10%65/10070/100 ✓

At a Glance

Founded20112018
HeadquartersSanta Clara County, CABrooklyn, NY
Publicly tradedNoNo
Treatment categories34
Treatments listed37
Starting price$50/mo$15/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryMuselyTwentyeight Health
Dermatology$50–$100
The Spot Cream
—
Women's Health—$15–$19.99
Complete Care Membership

Musely

+Strong Trustpilot rating (4.1/5 across ~2,300 reviews) relative to compounding-derm peers
+Broad and unusually varied catalog spanning pigmentation, anti-aging, hair loss, and menopause care
+Fast shipping and quick support response times are consistently cited
−Exact pricing per product isn't published; site only gives a broad $50-100/month range
−Subscription renewal system is described by patients as rigid and hard to adjust
−Nearly identical bottle labeling across different formulas has caused reordering confusion
Read the full Musely review →

Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance
+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do
+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours
−Medications are billed separately from the membership, which some reviewers say caused unexpected charges
−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states
−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems
Read the full Twentyeight Health review →

Musely vs Twentyeight Health — FAQ

Is Musely better than Twentyeight Health?

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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 67.9/100), leading on trust & safety, value, experience, reputation.

Is Musely or Twentyeight Health cheaper?

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Twentyeight Health has the lower starting price (from $15/mo vs $50/mo for Musely). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Musely and Twentyeight Health both offer?

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Both platforms treat Dermatology, Women's Health. Musely covers 3 treatment categories total and Twentyeight Health covers 4.

Still deciding?

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