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OrderlyMeds vs Twentyeight Health: Which Is Better?

Head-to-head comparison of OrderlyMeds and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 54.8/100), leading on trust & safety, value, experience, product range, reputation.

55
OrderlyMeds
Below Average

2024-founded compounded GLP-1 telehealth service with low entry pricing and add-on wellness perks, but a below-average Trustpilot track record.

Visit OrderlyMeds
75

Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

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Score Breakdown

DimensionOrderlyMedsTwentyeight Health
Overall Score54.8/10075/100 ✓
Trust & Safety30%55/10076/100 ✓
Value25%58/10080/100 ✓
Experience20%50/10072/100 ✓
Product Range15%62/10072/100 ✓
Reputation10%45/10070/100 ✓

At a Glance

Founded20242018
Headquarters—Brooklyn, NY
Publicly tradedNoNo
Treatment categories14
Treatments listed47
Starting price$74/mo$15/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryOrderlyMedsTwentyeight Health
Weight Loss / GLP-1$74–$149
Compounded Semaglutide
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OrderlyMeds

+Transparent about which named 503A pharmacies fulfill prescriptions
+Low advertised starter pricing ($74-149/mo) provides an accessible entry point
+Bundled extras (BetterHelp therapy access, Trifecta fitness app, nutrition guides) add value beyond medication
−Starter pricing roughly doubles after the first cycle ($74 to $149, $149 to $299/mo), which can surprise patients
−Trustpilot rating of only 3.6/5 with reports of shipping delays and heat-damaged packages
−A licensed pharmacist has publicly flagged concerns about the company's beyond-use-date prescribing practices
Read the full OrderlyMeds review →

Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance
+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do
+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours
−Medications are billed separately from the membership, which some reviewers say caused unexpected charges
−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states
−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems
Read the full Twentyeight Health review →

OrderlyMeds vs Twentyeight Health — FAQ

Is OrderlyMeds better than Twentyeight Health?

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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 54.8/100), leading on trust & safety, value, experience, product range, reputation.

Is OrderlyMeds or Twentyeight Health cheaper?

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Twentyeight Health has the lower starting price (from $15/mo vs $74/mo for OrderlyMeds). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do OrderlyMeds and Twentyeight Health both offer?

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Both platforms treat Weight Loss / GLP-1. OrderlyMeds covers 1 treatment category total and Twentyeight Health covers 4.

Still deciding?

OrderlyMeds alternativesTwentyeight Health alternativesTake the Match Quiz