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PlushCare vs ProlongMD: Which Is Better?

Head-to-head comparison of PlushCare and ProlongMD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

PlushCare scores higher overall in our independent evaluation (68.3/100 vs 60.1/100), leading on trust & safety, experience, reputation. ProlongMD comes out ahead on value, product range.

68

PlushCare is a virtual primary-care membership service that layers weight-loss visits and branded GLP-1 prescriptions onto its core telehealth offering, rather than running a dedicated compounded-GLP-1 program.

Visit PlushCare
60

Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

Visit ProlongMD

Score Breakdown

DimensionPlushCareProlongMD
Overall Score68.3/100 ✓60.1/100
Trust & Safety30%78/100 ✓52/100
Value25%62/10074/100 ✓
Experience20%62/100 ✓55/100
Product Range15%65/10070/100 ✓
Reputation10%72/100 ✓45/100

At a Glance

Founded20142025
HeadquartersSan Francisco, CAPhoenix, AZ
Publicly tradedNoNo
Treatment categories28
Treatments listed313
Starting price$20/mo$25/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryPlushCareProlongMD
Primary Care$20–$129
PlushCare Membership + Weight-Loss Visit
$79
Consultation (30-min video, credited toward treatment)
Weight Loss / GLP-1$650–$1100
Branded GLP-1 Prescription (Wegovy, Saxenda)
$99–$119
Compounded Semaglutide/B12

PlushCare

+Low $19.99/mo membership with first month free, and insurance-eligible visits as low as a $30 copay
+Accepts major insurance plans (Aetna, Cigna, Humana), broader than most single-purpose GLP-1 telehealth startups
+Physician-led primary care model covers ongoing and chronic care beyond a single weight-loss funnel
−Branded GLP-1 medication (Zepbound, Wegovy) is billed separately at the pharmacy — without insurance coverage this can run roughly $1,000+/month, dwarfing the low membership fee
−No compounded GLP-1 option, so cash-pay patients without drug coverage face full retail brand pricing
−Trustpilot pattern of unexpected recurring membership charges and difficulty cancelling
Read the full PlushCare review →

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee
+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs
+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits
−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form
−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)
−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text
Read the full ProlongMD review →

PlushCare vs ProlongMD — FAQ

Is PlushCare better than ProlongMD?

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PlushCare scores higher overall in our independent evaluation (68.3/100 vs 60.1/100), leading on trust & safety, experience, reputation. ProlongMD comes out ahead on value, product range.

Is PlushCare or ProlongMD cheaper?

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PlushCare has the lower starting price (from $20/mo vs $25/mo for ProlongMD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do PlushCare and ProlongMD both offer?

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Both platforms treat Primary Care, Weight Loss / GLP-1. PlushCare covers 2 treatment categories total and ProlongMD covers 8.

Still deciding?