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ProlongMD vs ReadyRx: Which Is Better?

Head-to-head comparison of ProlongMD and ReadyRx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

ReadyRx scores higher overall in our independent evaluation (63.3/100 vs 60.1/100), leading on trust & safety, experience, reputation. ProlongMD comes out ahead on value. ProlongMD has the lower entry price (from $25/mo vs $32/mo), so the better value depends on which treatment you need.

ProlongMD

Fair

Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

Visit ProlongMD

ReadyRx

Fair

ReadyRx is an Austin-based telehealth platform focused on sermorelin (injectable and ODT), NAD+, glutathione and compounded GLP-1s, with a large and largely positive Trustpilot base.

Visit ReadyRx

Score Breakdown

Dimension	ProlongMD	ReadyRx
Overall Score	60.1/100	63.3/100 ✓
Trust & Safety30%	52/100	58/100 ✓
Value25%	74/100 ✓	64/100
Experience20%	55/100	68/100 ✓
Product Range15%	70/100	70/100
Reputation10%	45/100	58/100 ✓

At a Glance

Founded	2025	2022
Headquarters	Phoenix, AZ	Austin, TX
Publicly traded	No	No
Treatment categories	8	2
Treatments listed	13	7
Starting price	$25/mo	$32/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

Category	ProlongMD	ReadyRx
Weight Loss / GLP-1	$99–$119 Compounded Semaglutide/B12	$32 Metformin (90-day program)
Longevity & Peptides	$179 Sermorelin	$80–$130 MIC+B12

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee

+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs

+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits

−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form

−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)

−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text

Read the full ProlongMD review →

ReadyRx

+Large, positive review base (4.7/5 on Trustpilot, about 1,050 reviews) citing fast shipping and responsive support

+Needle-free options across its longevity line: sermorelin ODT, NAD+ nasal spray, glutathione nasal spray

+Plans include unlimited provider messaging, coaching and free shipping; states that batches are third-party tested for potency, sterility and endotoxins

−Recurring 1-star complaints about difficult cancellation and shipments continuing after cancelling, including one report of being required to waive refunds to cancel

−Prices are not shown on treatment pages and only appear inside the checkout flow

−Billed every 28 days (13 charges a year); sermorelin rises from $146 to $190 after the first month

Read the full ReadyRx review →

ProlongMD vs ReadyRx — FAQ

Is ProlongMD better than ReadyRx?

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Is ProlongMD or ReadyRx cheaper?

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ProlongMD has the lower starting price (from $25/mo vs $32/mo for ReadyRx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do ProlongMD and ReadyRx both offer?

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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides. ProlongMD covers 8 treatment categories total and ReadyRx covers 2.

Still deciding?

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