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ProlongMD vs Rex MD: Which Is Better?

Head-to-head comparison of ProlongMD and Rex MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Rex MD scores higher overall in our independent evaluation (72.2/100 vs 60.1/100), leading on trust & safety, experience, product range, reputation. ProlongMD comes out ahead on value.

60

Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

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72
Rex MD
Good

Rex MD is a men's-health telehealth brand — owned by publicly traded LifeMD — covering ED, premature ejaculation, TRT, hair loss, and GLP-1 treatment.

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Score Breakdown

DimensionProlongMDRex MD
Overall Score60.1/10072.2/100 ✓
Trust & Safety30%52/10078/100 ✓
Value25%74/100 ✓65/100
Experience20%55/10068/100 ✓
Product Range15%70/10078/100 ✓
Reputation10%45/10072/100 ✓

At a Glance

Founded20252019
HeadquartersPhoenix, AZNew York, NY
Publicly tradedNoNo
Treatment categories85
Treatments listed136
Starting price$25/mo$2/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryProlongMDRex MD
Weight Loss / GLP-1$99–$119
Compounded Semaglutide/B12
$199–$399
GLP-1 Weight Loss
Hormone Therapy$89–$119
Testosterone Cypionate (200 mg/mL)
$79–$199
TRT (cypionate/gel/Clomid/sermorelin)
Men's Health$129–$159
Enclomiphene 25 mg
—
Sexual Health$75
Tadalafil 24 mg
$2–$90
Sildenafil / Tadalafil (generic & brand)
Hair Loss$25
Oral Finasteride 5 mg
$25–$45
Finasteride

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee
+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs
+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits
−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form
−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)
−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text
Read the full ProlongMD review →

Rex MD

+Backed by LifeMD, a publicly traded parent company, giving it more financial and compliance infrastructure than an independent startup
+Strong Trustpilot rating (4.7/5, 5,259 reviews) with consistent praise for customer service staff
+Wide medication range across ED, premature ejaculation, TRT, hair loss, and GLP-1s under one account
−Recurring patient complaints about surprise auto-renewal charges not clearly disclosed at checkout
−Shipping and fulfillment issues reported, including incorrect dosing and underfilled vials
−Headline 'as low as $2/dose' pricing is a teaser rate; full pricing isn't shown until after intake
Read the full Rex MD review →

ProlongMD vs Rex MD — FAQ

Is ProlongMD better than Rex MD?

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Rex MD scores higher overall in our independent evaluation (72.2/100 vs 60.1/100), leading on trust & safety, experience, product range, reputation. ProlongMD comes out ahead on value.

Is ProlongMD or Rex MD cheaper?

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Rex MD has the lower starting price (from $2/mo vs $25/mo for ProlongMD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do ProlongMD and Rex MD both offer?

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Both platforms treat Weight Loss / GLP-1, Hormone Therapy, Men's Health, Sexual Health, Hair Loss. ProlongMD covers 8 treatment categories total and Rex MD covers 5.

Still deciding?