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ProlongMD vs Sermorelin.com: Which Is Better?

Head-to-head comparison of ProlongMD and Sermorelin.com based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

ProlongMD scores higher overall in our independent evaluation (60.1/100 vs 58/100), leading on value, product range. Sermorelin.com comes out ahead on trust & safety, experience, reputation.

60

Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

Visit ProlongMD
58

Single-product telehealth brand that sells compounded sermorelin as a nightly injection or an under-the-tongue tablet, prescribed by a Florida-based medical group.

Visit Sermorelin.com

Score Breakdown

DimensionProlongMDSermorelin.com
Overall Score60.1/100 ✓58/100
Trust & Safety30%52/10060/100 ✓
Value25%74/100 ✓68/100
Experience20%55/10062/100 ✓
Product Range15%70/100 ✓36/100
Reputation10%45/10052/100 ✓

At a Glance

Founded2025—
HeadquartersPhoenix, AZSheridan, WY
Publicly tradedNoNo
Treatment categories81
Treatments listed132
Starting price$25/mo$149/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryProlongMDSermorelin.com
Longevity & Peptides$179
Sermorelin
$149–$199
Compounded Sermorelin Injection

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee
+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs
+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits
−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form
−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)
−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text
Read the full ProlongMD review →

Sermorelin.com

+All-in pricing shown before intake ($149-$199/mo) covers the physician consult, medication, supplies and free 2-day shipping
+Names its medical group (Wasef Health, PC, Michael Wasef MD) and dispensing pharmacy (SmartScripts / PerfectRx, Flower Mound, TX) on the site
+Offers injectable and sublingual tablet sermorelin at the same price, and says card holds are only charged after physician approval
−Only one drug is offered, so there are no labs, hormone therapy or other longevity treatments
−Operator is an anonymous Wyoming LLC at a registered-agent address; no named founders or clinical leadership beyond the contracted PC
−On-site testimonials name competitors (MaleMD, Eden) in a promotional way that cannot be independently verified
Read the full Sermorelin.com review →

ProlongMD vs Sermorelin.com — FAQ

Is ProlongMD better than Sermorelin.com?

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ProlongMD scores higher overall in our independent evaluation (60.1/100 vs 58/100), leading on value, product range. Sermorelin.com comes out ahead on trust & safety, experience, reputation.

Is ProlongMD or Sermorelin.com cheaper?

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ProlongMD has the lower starting price (from $25/mo vs $149/mo for Sermorelin.com). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do ProlongMD and Sermorelin.com both offer?

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Both platforms treat Longevity & Peptides. ProlongMD covers 8 treatment categories total and Sermorelin.com covers 1.

Still deciding?

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