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ProlongMD vs Shameless Care: Which Is Better?

Head-to-head comparison of ProlongMD and Shameless Care based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Shameless Care scores higher overall in our independent evaluation (66/100 vs 60.1/100), leading on trust & safety, experience, reputation. ProlongMD comes out ahead on value, product range. ProlongMD has the lower entry price (from $25/mo vs $63/mo), so the better value depends on which treatment you need.

60

Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

Visit ProlongMD
66

Shameless Care is an Illinois sexual-health telehealth company selling ED and female-arousal medications, comprehensive STI testing, DoxyPEP and UTI/BV/yeast treatment as one-time purchases.

Visit Shameless Care

Score Breakdown

DimensionProlongMDShameless Care
Overall Score60.1/10066/100 ✓
Trust & Safety30%52/10068/100 ✓
Value25%74/100 ✓68/100
Experience20%55/10066/100 ✓
Product Range15%70/100 ✓66/100
Reputation10%45/10055/100 ✓

At a Glance

Founded20252022
HeadquartersPhoenix, AZSt. Charles, IL
Publicly tradedNoNo
Treatment categories84
Treatments listed1310
Starting price$25/mo$63/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryProlongMDShameless Care
Men's Health$129–$159
Enclomiphene 25 mg
—
Women's Health$33
Progesterone (oral)
$63
UTI / BV / Yeast Infection Treatment
Sexual Health$75
Tadalafil 24 mg
$99–$199
DoxyPEP
Primary Care$79
Consultation (30-min video, credited toward treatment)
$279
14-Panel STI Testing

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee
+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs
+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits
−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form
−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)
−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text
Read the full ProlongMD review →

Shameless Care

+One-time purchases with no auto-renewal, which avoids the recurring-charge complaints common in the category
+Every price is posted on the site, all-in with consult, prescription and shipping (e.g. UTI treatment $63, Shameless Duo from $130)
+Covers men's and women's sexual health, including STI testing, DoxyPEP, herpes suppression and female arousal treatments, which most ED-focused brands don't
−Two of its three named partner pharmacies (Curexa, Belmar) received FDA compounding warning letters in 2023
−Review evidence is mostly the brand's own on-site testimonials; little independent Trustpilot or Reddit footprint
−Compounded ED troches cost about $7–11 per dose, well above generic sildenafil or tadalafil tablets
Read the full Shameless Care review →

ProlongMD vs Shameless Care — FAQ

Is ProlongMD better than Shameless Care?

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Shameless Care scores higher overall in our independent evaluation (66/100 vs 60.1/100), leading on trust & safety, experience, reputation. ProlongMD comes out ahead on value, product range. ProlongMD has the lower entry price (from $25/mo vs $63/mo), so the better value depends on which treatment you need.

Is ProlongMD or Shameless Care cheaper?

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ProlongMD has the lower starting price (from $25/mo vs $63/mo for Shameless Care). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do ProlongMD and Shameless Care both offer?

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Both platforms treat Men's Health, Women's Health, Sexual Health, Primary Care. ProlongMD covers 8 treatment categories total and Shameless Care covers 4.

Still deciding?

ProlongMD alternativesShameless Care alternativesTake the Match Quiz