Home›Compare›ProlongMD vs SkinnyRx

ProlongMD vs SkinnyRx: Which Is Better?

Head-to-head comparison of ProlongMD and SkinnyRx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

ProlongMD scores higher overall in our independent evaluation (60.1/100 vs 57.9/100), leading on trust & safety, value, product range, reputation. SkinnyRx comes out ahead on experience.

60

Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

Visit ProlongMD
58

Cash-pay compounded GLP-1 provider offering five dosing formats, currently facing an FDA warning letter against its parent company.

Visit SkinnyRx

Score Breakdown

DimensionProlongMDSkinnyRx
Overall Score60.1/100 ✓57.9/100
Trust & Safety30%52/100 ✓45/100
Value25%74/100 ✓68/100
Experience20%55/10078/100 ✓
Product Range15%70/100 ✓55/100
Reputation10%45/100 ✓35/100

At a Glance

Founded2025—
HeadquartersPhoenix, AZ—
Publicly tradedNoNo
Treatment categories81
Treatments listed134
Starting price$25/mo$199/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryProlongMDSkinnyRx
Weight Loss / GLP-1$99–$119
Compounded Semaglutide/B12
$199
Semaglutide Injection

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee
+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs
+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits
−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form
−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)
−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text
Read the full ProlongMD review →

SkinnyRx

+Five dosing formats (injection, sublingual, tablet) for semaglutide/tirzepatide give patients flexibility
+Large Trustpilot volume (5,390 reviews) at a 4.8 average suggests broad satisfaction
+Reps cited by name in reviews for responsive onboarding guidance
−FDA warning letter reportedly issued to parent company Lean Rx, Inc. (February 2026) — unverified independently this cycle, needs manual confirmation
−Some patients report oral/sublingual formats were ineffective with no visible results
−A reviewer described being required to pay upfront for medication that had no effect
Read the full SkinnyRx review →

ProlongMD vs SkinnyRx — FAQ

Is ProlongMD better than SkinnyRx?

▾

ProlongMD scores higher overall in our independent evaluation (60.1/100 vs 57.9/100), leading on trust & safety, value, product range, reputation. SkinnyRx comes out ahead on experience.

Is ProlongMD or SkinnyRx cheaper?

▾

ProlongMD has the lower starting price (from $25/mo vs $199/mo for SkinnyRx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do ProlongMD and SkinnyRx both offer?

▾

Both platforms treat Weight Loss / GLP-1. ProlongMD covers 8 treatment categories total and SkinnyRx covers 1.

Still deciding?

ProlongMD alternativesSkinnyRx alternativesTake the Match Quiz