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ProlongMD vs Syra Rx: Which Is Better?

Head-to-head comparison of ProlongMD and Syra Rx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

ProlongMD scores higher overall in our independent evaluation (60.1/100 vs 53.5/100), leading on trust & safety, value, experience, reputation.

60

Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

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54
Syra Rx
Below Average

Syra Rx is a 2026-launched, affiliate-distributed telehealth storefront for compounded GLP-1s, NAD+, sermorelin, tesamorelin and ED treatment, with clinical care outsourced to LocumTele and fulfillment by Rush Pharmacy.

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Score Breakdown

DimensionProlongMDSyra Rx
Overall Score60.1/100 ✓53.5/100
Trust & Safety30%52/100 ✓50/100
Value25%74/100 ✓56/100
Experience20%55/100 ✓50/100
Product Range15%70/10070/100
Reputation10%45/100 ✓40/100

At a Glance

Founded20252026
HeadquartersPhoenix, AZ—
Publicly tradedNoNo
Treatment categories83
Treatments listed135
Starting price$25/mo$30/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryProlongMDSyra Rx
Weight Loss / GLP-1$99–$119
Compounded Semaglutide/B12
$199–$399
Compounded GLP-1 (semaglutide/tirzepatide)
Sexual Health$75
Tadalafil 24 mg
$30–$100
ED Treatment
Longevity & Peptides$179
Sermorelin
$150–$250
Compounded Sermorelin

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee
+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs
+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits
−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form
−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)
−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text
Read the full ProlongMD review →

Syra Rx

+Discloses its provider network (LocumTele) and dispensing pharmacy (Rush Pharmacy) by name in the FAQ
+One of few consumer brands offering tesamorelin alongside sermorelin and NAD+
+States a fast fulfillment window (usually 1–2 business days after approval)
−No prices published anywhere on the site; costs appear only inside third-party intake funnels
−Launched in 2026 with no independent patient reviews and no physical address disclosed
−Terms of service cover only GLP-1 services even though the site markets peptides, NAD+ and ED treatment
Read the full Syra Rx review →

ProlongMD vs Syra Rx — FAQ

Is ProlongMD better than Syra Rx?

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ProlongMD scores higher overall in our independent evaluation (60.1/100 vs 53.5/100), leading on trust & safety, value, experience, reputation.

Is ProlongMD or Syra Rx cheaper?

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ProlongMD has the lower starting price (from $25/mo vs $30/mo for Syra Rx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do ProlongMD and Syra Rx both offer?

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Both platforms treat Weight Loss / GLP-1, Sexual Health, Longevity & Peptides. ProlongMD covers 8 treatment categories total and Syra Rx covers 3.

Still deciding?

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