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ProlongMD vs TrimRx: Which Is Better?

Head-to-head comparison of ProlongMD and TrimRx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

ProlongMD scores higher overall in our independent evaluation (60.1/100 vs 52/100), leading on value, experience, product range. TrimRx comes out ahead on trust & safety.

60

Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

Visit ProlongMD
52
TrimRx
Below Average

San Diego-based GLP-1 weight loss telehealth offering compounded semaglutide and tirzepatide at $179-349/month.

Visit TrimRx

Score Breakdown

DimensionProlongMDTrimRx
Overall Score60.1/100 ✓52/100
Trust & Safety30%52/10055/100 ✓
Value25%74/100 ✓70/100
Experience20%55/100 ✓45/100
Product Range15%70/100 ✓30/100
Reputation10%45/10045/100

At a Glance

Founded20252024
HeadquartersPhoenix, AZSan Diego, CA
Publicly tradedNoNo
Treatment categories81
Treatments listed138
Starting price$25/mo$179/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryProlongMDTrimRx
Weight Loss / GLP-1$99–$119
Compounded Semaglutide/B12
$179–$329
Compounded Semaglutide (Oral/Sublingual)

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee
+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs
+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits
−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form
−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)
−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text
Read the full ProlongMD review →

TrimRx

+70-85% savings vs brand-name GLP-1s: semaglutide at $199/mo vs $1,000+ retail
+Not included in FDA's 2025 warning letter wave — clean regulatory record
+Multiple delivery formats: injectable, oral tablet, and sublingual drops
−Branded pages advertise 'In Stock' with a price while the same page states TrimRx does not sell, dispense or ship branded medication and the patient pays a pharmacy directly
−Cancellation difficulties: long phone waits, reports of being hung up on; dedicated JoinChargeback page exists
−Strict no-refund policy once medical intake is submitted, even before medication ships
Read the full TrimRx review →

ProlongMD vs TrimRx — FAQ

Is ProlongMD better than TrimRx?

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ProlongMD scores higher overall in our independent evaluation (60.1/100 vs 52/100), leading on value, experience, product range. TrimRx comes out ahead on trust & safety.

Is ProlongMD or TrimRx cheaper?

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ProlongMD has the lower starting price (from $25/mo vs $179/mo for TrimRx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do ProlongMD and TrimRx both offer?

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Both platforms treat Weight Loss / GLP-1. ProlongMD covers 8 treatment categories total and TrimRx covers 1.

Still deciding?

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