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ProlongMD vs Willow: Which Is Better?

Head-to-head comparison of ProlongMD and Willow based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

ProlongMD scores higher overall in our independent evaluation (60.1/100 vs 51.9/100), leading on trust & safety, value, product range, reputation. Willow comes out ahead on experience.

60

Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

Visit ProlongMD
52
Willow
Below Average

Women-focused compounded GLP-1 telehealth brand operating in a limited number of states, tied to a National Advertising Division referral over its marketing claims.

Visit Willow

Score Breakdown

DimensionProlongMDWillow
Overall Score60.1/100 ✓51.9/100
Trust & Safety30%52/100 ✓48/100
Value25%74/100 ✓52/100
Experience20%55/10062/100 ✓
Product Range15%70/100 ✓55/100
Reputation10%45/100 ✓38/100

At a Glance

Founded2025—
HeadquartersPhoenix, AZ—
Publicly tradedNoNo
Treatment categories82
Treatments listed132
Starting price$25/mo$299/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryProlongMDWillow
Weight Loss / GLP-1$99–$119
Compounded Semaglutide/B12
$299
Compounded Semaglutide
Women's Health$33
Progesterone (oral)
—

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee
+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs
+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits
−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form
−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)
−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text
Read the full ProlongMD review →

Willow

+Women-focused positioning with unlimited doctor access included in plan price
+Reviewers highlight responsive, board-certified doctors and simple onboarding
+Some patients report substantial results (e.g., 65 lbs in three months)
−Reportedly referred by the National Advertising Division to state attorneys general (Dec 2025) over advertising claims — unverified independently this cycle, needs manual confirmation
−Service limited to a narrow footprint (reportedly ~12 states), well below most national competitors
−Pricing ($299-399/mo starting) runs higher than several direct compounded-GLP-1 competitors
Read the full Willow review →

ProlongMD vs Willow — FAQ

Is ProlongMD better than Willow?

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ProlongMD scores higher overall in our independent evaluation (60.1/100 vs 51.9/100), leading on trust & safety, value, product range, reputation. Willow comes out ahead on experience.

Is ProlongMD or Willow cheaper?

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ProlongMD has the lower starting price (from $25/mo vs $299/mo for Willow). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do ProlongMD and Willow both offer?

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Both platforms treat Weight Loss / GLP-1, Women's Health. ProlongMD covers 8 treatment categories total and Willow covers 2.

Still deciding?

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