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ProlongMD vs XYON Health: Which Is Better?

Head-to-head comparison of ProlongMD and XYON Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

XYON Health scores higher overall in our independent evaluation (65.9/100 vs 60.1/100), leading on trust & safety, experience, reputation. ProlongMD comes out ahead on value, product range. ProlongMD has the lower entry price (from $25/mo vs $109/mo), so the better value depends on which treatment you need.

60

Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

Visit ProlongMD
66

Physician-led hair loss telehealth brand co-founded by hair transplant surgeons, specializing in topical finasteride and combination scalp formulas.

Visit XYON Health

Score Breakdown

DimensionProlongMDXYON Health
Overall Score60.1/10065.9/100 ✓
Trust & Safety30%52/10068/100 ✓
Value25%74/100 ✓62/100
Experience20%55/10064/100 ✓
Product Range15%70/100 ✓68/100
Reputation10%45/10070/100 ✓

At a Glance

Founded20252019
HeadquartersPhoenix, AZVancouver, BC, Canada
Publicly tradedNoNo
Treatment categories83
Treatments listed133
Starting price$25/mo$109/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryProlongMDXYON Health
Men's Health$129–$159
Enclomiphene 25 mg
—
Women's Health$33
Progesterone (oral)
—
Hair Loss$25
Oral Finasteride 5 mg
$109–$119
Topical Finasteride Gel

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee
+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs
+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits
−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form
−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)
−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text
Read the full ProlongMD review →

XYON Health

+Co-founded by established hair transplant surgeons, lending clinical credibility to formulation choices
+One of the most-discussed topical finasteride brands in the r/tressless community
+Broad hair-loss formulation range: topical finasteride, topical dutasteride, combination gel, and oral options
−Small Trustpilot sample (65 reviews) limits confidence in the 3.7/5 rating
−Topical gel texture ('sticky,' hard to apply) is a recurring patient complaint
−No live communication channel with prescribing clinicians reported by several patients
Read the full XYON Health review →

ProlongMD vs XYON Health — FAQ

Is ProlongMD better than XYON Health?

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XYON Health scores higher overall in our independent evaluation (65.9/100 vs 60.1/100), leading on trust & safety, experience, reputation. ProlongMD comes out ahead on value, product range. ProlongMD has the lower entry price (from $25/mo vs $109/mo), so the better value depends on which treatment you need.

Is ProlongMD or XYON Health cheaper?

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ProlongMD has the lower starting price (from $25/mo vs $109/mo for XYON Health). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do ProlongMD and XYON Health both offer?

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Both platforms treat Men's Health, Women's Health, Hair Loss. ProlongMD covers 8 treatment categories total and XYON Health covers 3.

Still deciding?

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