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Rex MD vs RxSpan MD: Which Is Better?

Head-to-head comparison of Rex MD and RxSpan MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Rex MD scores higher overall in our independent evaluation (72.2/100 vs 59.1/100), leading on trust & safety, value, experience, reputation.

72
Rex MD
Good

Rex MD is a men's-health telehealth brand — owned by publicly traded LifeMD — covering ED, premature ejaculation, TRT, hair loss, and GLP-1 treatment.

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59

RxSpan MD is a Beverly Hills telehealth practice founded by a plastic surgeon, offering compounded and branded GLP-1s, longevity peptides, hair-loss and ED treatment.

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Score Breakdown

DimensionRex MDRxSpan MD
Overall Score72.2/100 ✓59.1/100
Trust & Safety30%78/100 ✓60/100
Value25%65/100 ✓58/100
Experience20%68/100 ✓52/100
Product Range15%78/10078/100
Reputation10%72/100 ✓45/100

At a Glance

Founded20192026
HeadquartersNew York, NYBeverly Hills, CA
Publicly tradedNoNo
Treatment categories54
Treatments listed69
Starting price$2/mo$30/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryRex MDRxSpan MD
Sexual Health$2–$90
Sildenafil / Tadalafil (generic & brand)
$30–$100
ED (tadalafil, sildenafil/pycnogenol, vardenafil)
Hair Loss$25–$45
Finasteride
$30–$80
Hair Loss (oral minoxidil, finasteride/minoxidil, dutasteride)
Weight Loss / GLP-1$199–$399
GLP-1 Weight Loss
$249–$299
Compounded Semaglutide (injection or oral)

Rex MD

+Backed by LifeMD, a publicly traded parent company, giving it more financial and compliance infrastructure than an independent startup
+Strong Trustpilot rating (4.7/5, 5,259 reviews) with consistent praise for customer service staff
+Wide medication range across ED, premature ejaculation, TRT, hair loss, and GLP-1s under one account
−Recurring patient complaints about surprise auto-renewal charges not clearly disclosed at checkout
−Shipping and fulfillment issues reported, including incorrect dosing and underfilled vials
−Headline 'as low as $2/dose' pricing is a teaser rate; full pricing isn't shown until after intake
Read the full Rex MD review →

RxSpan MD

+Physician-founded practice with a named founder and a stated Beverly Hills address
+Offers both compounded (injection and oral) and branded GLP-1s, including cash-pay Zepbound listed at $500
+Third-party coverage reports named 503A pharmacy partners and free expedited shipping
−Compounded prices aren't visible on the public site; its product catalog failed to load during our research
−Brand-stated first-month prices ($249 semaglutide, $329 tirzepatide) are above peer averages, and renewal pricing is not published
−Site configuration shows an $80 initial visit fee that is not prominently disclosed
Read the full RxSpan MD review →

Rex MD vs RxSpan MD — FAQ

Is Rex MD better than RxSpan MD?

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Rex MD scores higher overall in our independent evaluation (72.2/100 vs 59.1/100), leading on trust & safety, value, experience, reputation.

Is Rex MD or RxSpan MD cheaper?

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Rex MD has the lower starting price (from $2/mo vs $30/mo for RxSpan MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Rex MD and RxSpan MD both offer?

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Both platforms treat Sexual Health, Hair Loss, Weight Loss / GLP-1. Rex MD covers 5 treatment categories total and RxSpan MD covers 4.

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