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RxSpan MD vs Sesame Care: Which Is Better?

Head-to-head comparison of RxSpan MD and Sesame Care based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Sesame Care scores higher overall in our independent evaluation (74/100 vs 59.1/100), leading on trust & safety, value, experience, reputation. RxSpan MD comes out ahead on product range.

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RxSpan MD is a Beverly Hills telehealth practice founded by a plastic surgeon, offering compounded and branded GLP-1s, longevity peptides, hair-loss and ED treatment.

Visit RxSpan MD
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Pay-per-visit marketplace connecting patients with licensed providers — no subscriptions, transparent per-visit pricing.

Visit Sesame Care

Score Breakdown

DimensionRxSpan MDSesame Care
Overall Score59.1/10074/100 ✓
Trust & Safety30%60/10075/100 ✓
Value25%58/10080/100 ✓
Experience20%52/10070/100 ✓
Product Range15%78/100 ✓70/100
Reputation10%45/10070/100 ✓

At a Glance

Founded20262019
HeadquartersBeverly Hills, CANew York, NY
Publicly tradedNoNo
Treatment categories46
Treatments listed97
Starting price$30/mo$11/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryRxSpan MDSesame Care
Weight Loss / GLP-1$249–$299
Compounded Semaglutide (injection or oral)
$59–$99
Weight Loss Program (subscription)

RxSpan MD

+Physician-founded practice with a named founder and a stated Beverly Hills address
+Offers both compounded (injection and oral) and branded GLP-1s, including cash-pay Zepbound listed at $500
+Third-party coverage reports named 503A pharmacy partners and free expedited shipping
−Compounded prices aren't visible on the public site; its product catalog failed to load during our research
−Brand-stated first-month prices ($249 semaglutide, $329 tirzepatide) are above peer averages, and renewal pricing is not published
−Site configuration shows an $80 initial visit fee that is not prominently disclosed
Read the full RxSpan MD review →

Sesame Care

+No subscription required — pay-per-visit model
+Transparent pricing shown before booking
+Wide range of specialties available
−No integrated pharmacy
−Less continuity of care than subscriptions
−Provider quality varies in marketplace model
Read the full Sesame Care review →

RxSpan MD vs Sesame Care — FAQ

Is RxSpan MD better than Sesame Care?

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Sesame Care scores higher overall in our independent evaluation (74/100 vs 59.1/100), leading on trust & safety, value, experience, reputation. RxSpan MD comes out ahead on product range.

Is RxSpan MD or Sesame Care cheaper?

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Sesame Care has the lower starting price (from $11/mo vs $30/mo for RxSpan MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do RxSpan MD and Sesame Care both offer?

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Both platforms treat Weight Loss / GLP-1. RxSpan MD covers 4 treatment categories total and Sesame Care covers 6.

Still deciding?

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