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RxSpan MD vs SkinnyRx: Which Is Better?

Head-to-head comparison of RxSpan MD and SkinnyRx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

RxSpan MD scores higher overall in our independent evaluation (59.1/100 vs 57.9/100), leading on trust & safety, product range, reputation. SkinnyRx comes out ahead on value, experience.

59

RxSpan MD is a Beverly Hills telehealth practice founded by a plastic surgeon, offering compounded and branded GLP-1s, longevity peptides, hair-loss and ED treatment.

Visit RxSpan MD
58

Cash-pay compounded GLP-1 provider offering five dosing formats, currently facing an FDA warning letter against its parent company.

Visit SkinnyRx

Score Breakdown

DimensionRxSpan MDSkinnyRx
Overall Score59.1/100 ✓57.9/100
Trust & Safety30%60/100 ✓45/100
Value25%58/10068/100 ✓
Experience20%52/10078/100 ✓
Product Range15%78/100 ✓55/100
Reputation10%45/100 ✓35/100

At a Glance

Founded2026—
HeadquartersBeverly Hills, CA—
Publicly tradedNoNo
Treatment categories41
Treatments listed94
Starting price$30/mo$199/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryRxSpan MDSkinnyRx
Weight Loss / GLP-1$249–$299
Compounded Semaglutide (injection or oral)
$199
Semaglutide Injection

RxSpan MD

+Physician-founded practice with a named founder and a stated Beverly Hills address
+Offers both compounded (injection and oral) and branded GLP-1s, including cash-pay Zepbound listed at $500
+Third-party coverage reports named 503A pharmacy partners and free expedited shipping
−Compounded prices aren't visible on the public site; its product catalog failed to load during our research
−Brand-stated first-month prices ($249 semaglutide, $329 tirzepatide) are above peer averages, and renewal pricing is not published
−Site configuration shows an $80 initial visit fee that is not prominently disclosed
Read the full RxSpan MD review →

SkinnyRx

+Five dosing formats (injection, sublingual, tablet) for semaglutide/tirzepatide give patients flexibility
+Large Trustpilot volume (5,390 reviews) at a 4.8 average suggests broad satisfaction
+Reps cited by name in reviews for responsive onboarding guidance
−FDA warning letter reportedly issued to parent company Lean Rx, Inc. (February 2026) — unverified independently this cycle, needs manual confirmation
−Some patients report oral/sublingual formats were ineffective with no visible results
−A reviewer described being required to pay upfront for medication that had no effect
Read the full SkinnyRx review →

RxSpan MD vs SkinnyRx — FAQ

Is RxSpan MD better than SkinnyRx?

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RxSpan MD scores higher overall in our independent evaluation (59.1/100 vs 57.9/100), leading on trust & safety, product range, reputation. SkinnyRx comes out ahead on value, experience.

Is RxSpan MD or SkinnyRx cheaper?

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RxSpan MD has the lower starting price (from $30/mo vs $199/mo for SkinnyRx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do RxSpan MD and SkinnyRx both offer?

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Both platforms treat Weight Loss / GLP-1. RxSpan MD covers 4 treatment categories total and SkinnyRx covers 1.

Still deciding?

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