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RxSpan MD vs Syra Rx: Which Is Better?

Head-to-head comparison of RxSpan MD and Syra Rx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

RxSpan MD scores higher overall in our independent evaluation (59.1/100 vs 53.5/100), leading on trust & safety, value, experience, product range, reputation.

59

RxSpan MD is a Beverly Hills telehealth practice founded by a plastic surgeon, offering compounded and branded GLP-1s, longevity peptides, hair-loss and ED treatment.

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54
Syra Rx
Below Average

Syra Rx is a 2026-launched, affiliate-distributed telehealth storefront for compounded GLP-1s, NAD+, sermorelin, tesamorelin and ED treatment, with clinical care outsourced to LocumTele and fulfillment by Rush Pharmacy.

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Score Breakdown

DimensionRxSpan MDSyra Rx
Overall Score59.1/100 ✓53.5/100
Trust & Safety30%60/100 ✓50/100
Value25%58/100 ✓56/100
Experience20%52/100 ✓50/100
Product Range15%78/100 ✓70/100
Reputation10%45/100 ✓40/100

At a Glance

Founded20262026
HeadquartersBeverly Hills, CA—
Publicly tradedNoNo
Treatment categories43
Treatments listed95
Starting price$30/mo$30/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryRxSpan MDSyra Rx
Weight Loss / GLP-1$249–$299
Compounded Semaglutide (injection or oral)
$199–$399
Compounded GLP-1 (semaglutide/tirzepatide)
Longevity & Peptides$100–$200
Glutathione
$150–$250
Compounded Sermorelin
Sexual Health$30–$100
ED (tadalafil, sildenafil/pycnogenol, vardenafil)
$30–$100
ED Treatment

RxSpan MD

+Physician-founded practice with a named founder and a stated Beverly Hills address
+Offers both compounded (injection and oral) and branded GLP-1s, including cash-pay Zepbound listed at $500
+Third-party coverage reports named 503A pharmacy partners and free expedited shipping
−Compounded prices aren't visible on the public site; its product catalog failed to load during our research
−Brand-stated first-month prices ($249 semaglutide, $329 tirzepatide) are above peer averages, and renewal pricing is not published
−Site configuration shows an $80 initial visit fee that is not prominently disclosed
Read the full RxSpan MD review →

Syra Rx

+Discloses its provider network (LocumTele) and dispensing pharmacy (Rush Pharmacy) by name in the FAQ
+One of few consumer brands offering tesamorelin alongside sermorelin and NAD+
+States a fast fulfillment window (usually 1–2 business days after approval)
−No prices published anywhere on the site; costs appear only inside third-party intake funnels
−Launched in 2026 with no independent patient reviews and no physical address disclosed
−Terms of service cover only GLP-1 services even though the site markets peptides, NAD+ and ED treatment
Read the full Syra Rx review →

RxSpan MD vs Syra Rx — FAQ

Is RxSpan MD better than Syra Rx?

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RxSpan MD scores higher overall in our independent evaluation (59.1/100 vs 53.5/100), leading on trust & safety, value, experience, product range, reputation.

Is RxSpan MD or Syra Rx cheaper?

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Their entry prices are similar — both start around $30/mo. Real cost depends on the specific treatment: compare the pricing tables on each review, since inclusions like consults, labs, and shipping differ.

What do RxSpan MD and Syra Rx both offer?

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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides, Sexual Health. RxSpan MD covers 4 treatment categories total and Syra Rx covers 3.

Still deciding?

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