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RxSpan MD vs System Labs: Which Is Better?

Head-to-head comparison of RxSpan MD and System Labs based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

RxSpan MD scores higher overall in our independent evaluation (59.1/100 vs 56.4/100), leading on trust & safety, product range. System Labs comes out ahead on value, experience.

59

RxSpan MD is a Beverly Hills telehealth practice founded by a plastic surgeon, offering compounded and branded GLP-1s, longevity peptides, hair-loss and ED treatment.

Visit RxSpan MD
56

System Labs is a San Francisco-based telehealth service prescribing compounded NAD+, sermorelin, glutathione and MIC-B12, with half-price first months.

Visit System Labs

Score Breakdown

DimensionRxSpan MDSystem Labs
Overall Score59.1/100 ✓56.4/100
Trust & Safety30%60/100 ✓52/100
Value25%58/10068/100 ✓
Experience20%52/10055/100 ✓
Product Range15%78/100 ✓55/100
Reputation10%45/10045/100

At a Glance

Founded2026—
HeadquartersBeverly Hills, CASan Francisco, CA
Publicly tradedNoNo
Treatment categories41
Treatments listed96
Starting price$30/mo$89/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryRxSpan MDSystem Labs
Longevity & Peptides$100–$200
Glutathione
$89
MIC+B12 Injection

RxSpan MD

+Physician-founded practice with a named founder and a stated Beverly Hills address
+Offers both compounded (injection and oral) and branded GLP-1s, including cash-pay Zepbound listed at $500
+Third-party coverage reports named 503A pharmacy partners and free expedited shipping
−Compounded prices aren't visible on the public site; its product catalog failed to load during our research
−Brand-stated first-month prices ($249 semaglutide, $329 tirzepatide) are above peer averages, and renewal pricing is not published
−Site configuration shows an $80 initial visit fee that is not prominently disclosed
Read the full RxSpan MD review →

System Labs

+Every price is posted on the site, including a first-month discount of roughly 40–50%
+Names its main compounding pharmacy (The Pharmacy Hub, Miami) and three board-certified physician advisors
+Both injectable and non-injectable options (NAD+ nasal spray, oral sermorelin)
−Trustpilot removed its business profile for guideline violations, so there is no independent review base
−'20k+ patients' claim is unverified; founding date and company history are not disclosed
−All sales are final once shipped; terms impose binding arbitration and a class-action waiver
Read the full System Labs review →

RxSpan MD vs System Labs — FAQ

Is RxSpan MD better than System Labs?

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RxSpan MD scores higher overall in our independent evaluation (59.1/100 vs 56.4/100), leading on trust & safety, product range. System Labs comes out ahead on value, experience.

Is RxSpan MD or System Labs cheaper?

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RxSpan MD has the lower starting price (from $30/mo vs $89/mo for System Labs). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do RxSpan MD and System Labs both offer?

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Both platforms treat Longevity & Peptides. RxSpan MD covers 4 treatment categories total and System Labs covers 1.

Still deciding?

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