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RxSpan MD vs Willow: Which Is Better?

Head-to-head comparison of RxSpan MD and Willow based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

RxSpan MD scores higher overall in our independent evaluation (59.1/100 vs 51.9/100), leading on trust & safety, value, product range, reputation. Willow comes out ahead on experience.

59

RxSpan MD is a Beverly Hills telehealth practice founded by a plastic surgeon, offering compounded and branded GLP-1s, longevity peptides, hair-loss and ED treatment.

Visit RxSpan MD
52
Willow
Below Average

Women-focused compounded GLP-1 telehealth brand operating in a limited number of states, tied to a National Advertising Division referral over its marketing claims.

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Score Breakdown

DimensionRxSpan MDWillow
Overall Score59.1/100 ✓51.9/100
Trust & Safety30%60/100 ✓48/100
Value25%58/100 ✓52/100
Experience20%52/10062/100 ✓
Product Range15%78/100 ✓55/100
Reputation10%45/100 ✓38/100

At a Glance

Founded2026—
HeadquartersBeverly Hills, CA—
Publicly tradedNoNo
Treatment categories42
Treatments listed92
Starting price$30/mo$299/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryRxSpan MDWillow
Weight Loss / GLP-1$249–$299
Compounded Semaglutide (injection or oral)
$299
Compounded Semaglutide

RxSpan MD

+Physician-founded practice with a named founder and a stated Beverly Hills address
+Offers both compounded (injection and oral) and branded GLP-1s, including cash-pay Zepbound listed at $500
+Third-party coverage reports named 503A pharmacy partners and free expedited shipping
−Compounded prices aren't visible on the public site; its product catalog failed to load during our research
−Brand-stated first-month prices ($249 semaglutide, $329 tirzepatide) are above peer averages, and renewal pricing is not published
−Site configuration shows an $80 initial visit fee that is not prominently disclosed
Read the full RxSpan MD review →

Willow

+Women-focused positioning with unlimited doctor access included in plan price
+Reviewers highlight responsive, board-certified doctors and simple onboarding
+Some patients report substantial results (e.g., 65 lbs in three months)
−Reportedly referred by the National Advertising Division to state attorneys general (Dec 2025) over advertising claims — unverified independently this cycle, needs manual confirmation
−Service limited to a narrow footprint (reportedly ~12 states), well below most national competitors
−Pricing ($299-399/mo starting) runs higher than several direct compounded-GLP-1 competitors
Read the full Willow review →

RxSpan MD vs Willow — FAQ

Is RxSpan MD better than Willow?

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RxSpan MD scores higher overall in our independent evaluation (59.1/100 vs 51.9/100), leading on trust & safety, value, product range, reputation. Willow comes out ahead on experience.

Is RxSpan MD or Willow cheaper?

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RxSpan MD has the lower starting price (from $30/mo vs $299/mo for Willow). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do RxSpan MD and Willow both offer?

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Both platforms treat Weight Loss / GLP-1. RxSpan MD covers 4 treatment categories total and Willow covers 2.

Still deciding?

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