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RxSpan MD vs XYON Health: Which Is Better?

Head-to-head comparison of RxSpan MD and XYON Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

XYON Health scores higher overall in our independent evaluation (65.9/100 vs 59.1/100), leading on trust & safety, value, experience, reputation. RxSpan MD comes out ahead on product range. RxSpan MD has the lower entry price (from $30/mo vs $109/mo), so the better value depends on which treatment you need.

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RxSpan MD is a Beverly Hills telehealth practice founded by a plastic surgeon, offering compounded and branded GLP-1s, longevity peptides, hair-loss and ED treatment.

Visit RxSpan MD
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Physician-led hair loss telehealth brand co-founded by hair transplant surgeons, specializing in topical finasteride and combination scalp formulas.

Visit XYON Health

Score Breakdown

DimensionRxSpan MDXYON Health
Overall Score59.1/10065.9/100 ✓
Trust & Safety30%60/10068/100 ✓
Value25%58/10062/100 ✓
Experience20%52/10064/100 ✓
Product Range15%78/100 ✓68/100
Reputation10%45/10070/100 ✓

At a Glance

Founded20262019
HeadquartersBeverly Hills, CAVancouver, BC, Canada
Publicly tradedNoNo
Treatment categories43
Treatments listed93
Starting price$30/mo$109/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryRxSpan MDXYON Health
Hair Loss$30–$80
Hair Loss (oral minoxidil, finasteride/minoxidil, dutasteride)
$109–$119
Topical Finasteride Gel

RxSpan MD

+Physician-founded practice with a named founder and a stated Beverly Hills address
+Offers both compounded (injection and oral) and branded GLP-1s, including cash-pay Zepbound listed at $500
+Third-party coverage reports named 503A pharmacy partners and free expedited shipping
−Compounded prices aren't visible on the public site; its product catalog failed to load during our research
−Brand-stated first-month prices ($249 semaglutide, $329 tirzepatide) are above peer averages, and renewal pricing is not published
−Site configuration shows an $80 initial visit fee that is not prominently disclosed
Read the full RxSpan MD review →

XYON Health

+Co-founded by established hair transplant surgeons, lending clinical credibility to formulation choices
+One of the most-discussed topical finasteride brands in the r/tressless community
+Broad hair-loss formulation range: topical finasteride, topical dutasteride, combination gel, and oral options
−Small Trustpilot sample (65 reviews) limits confidence in the 3.7/5 rating
−Topical gel texture ('sticky,' hard to apply) is a recurring patient complaint
−No live communication channel with prescribing clinicians reported by several patients
Read the full XYON Health review →

RxSpan MD vs XYON Health — FAQ

Is RxSpan MD better than XYON Health?

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XYON Health scores higher overall in our independent evaluation (65.9/100 vs 59.1/100), leading on trust & safety, value, experience, reputation. RxSpan MD comes out ahead on product range. RxSpan MD has the lower entry price (from $30/mo vs $109/mo), so the better value depends on which treatment you need.

Is RxSpan MD or XYON Health cheaper?

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RxSpan MD has the lower starting price (from $30/mo vs $109/mo for XYON Health). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do RxSpan MD and XYON Health both offer?

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Both platforms treat Hair Loss. RxSpan MD covers 4 treatment categories total and XYON Health covers 3.

Still deciding?

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