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RxSpan MD vs Yucca Health: Which Is Better?

Head-to-head comparison of RxSpan MD and Yucca Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Yucca Health scores higher overall in our independent evaluation (68.3/100 vs 59.1/100), leading on trust & safety, value, experience, reputation. RxSpan MD comes out ahead on product range. RxSpan MD has the lower entry price (from $30/mo vs $125/mo), so the better value depends on which treatment you need.

RxSpan MD

Fair

RxSpan MD is a Beverly Hills telehealth practice founded by a plastic surgeon, offering compounded and branded GLP-1s, longevity peptides, hair-loss and ED treatment.

Visit RxSpan MD

Yucca Health

Good

Yucca Health is a Beverly Hills-based telehealth platform selling compounded semaglutide and tirzepatide at flat, dose-independent prices, plus compounded NAD+ and sermorelin.

Visit Yucca Health

Score Breakdown

Dimension	RxSpan MD	Yucca Health
Overall Score	59.1/100	68.3/100 ✓
Trust & Safety30%	60/100	64/100 ✓
Value25%	58/100	80/100 ✓
Experience20%	52/100	72/100 ✓
Product Range15%	78/100 ✓	58/100
Reputation10%	45/100	60/100 ✓

At a Glance

Founded	2026	2025
Headquarters	Beverly Hills, CA	Beverly Hills, CA
Publicly traded	No	No
Treatment categories	4	2
Treatments listed	9	4
Starting price	$30/mo	$125/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

Category	RxSpan MD	Yucca Health
Weight Loss / GLP-1	$249–$299 Compounded Semaglutide (injection or oral)	$125–$146 Compounded Semaglutide+ (injectable)
Longevity & Peptides	$100–$200 Glutathione	$158–$215 NAD+ Injection

RxSpan MD

+Physician-founded practice with a named founder and a stated Beverly Hills address

+Offers both compounded (injection and oral) and branded GLP-1s, including cash-pay Zepbound listed at $500

+Third-party coverage reports named 503A pharmacy partners and free expedited shipping

−Compounded prices aren't visible on the public site; its product catalog failed to load during our research

−Brand-stated first-month prices ($249 semaglutide, $329 tirzepatide) are above peer averages, and renewal pricing is not published

−Site configuration shows an $80 initial visit fee that is not prominently disclosed

Read the full RxSpan MD review →

Yucca Health

+Full price grid published before intake: semaglutide $146/mo monthly, $140/mo quarterly or $125/mo on a 6-month prepay; tirzepatide $258, $248 or $225/mo

+Locked pricing covers the whole dose range, so titrating up does not raise the bill; pausing keeps the locked rate

+No separate membership or consultation fee; plans include the provider consult, medication, injection supplies and free 2-day shipping

−Dispensing pharmacies are not named on the public site; they appear only in the patient portal and on the label after ordering

−BBB rating of C+ (not accredited) with five closed complaints; one Trustpilot reviewer reports prepaying six months and receiving three

−About 6% of roughly 1,230 Trustpilot reviews are 1-star, citing lack of results after months of treatment and refund disputes

Read the full Yucca Health review →

RxSpan MD vs Yucca Health — FAQ

Is RxSpan MD better than Yucca Health?

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Is RxSpan MD or Yucca Health cheaper?

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RxSpan MD has the lower starting price (from $30/mo vs $125/mo for Yucca Health). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do RxSpan MD and Yucca Health both offer?

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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides. RxSpan MD covers 4 treatment categories total and Yucca Health covers 2.

Still deciding?

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