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Sesame Care vs Twentyeight Health: Which Is Better?

Head-to-head comparison of Sesame Care and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 74/100), leading on trust & safety, experience, product range. Sesame Care has the lower entry price (from $11/mo vs $15/mo), so the better value depends on which treatment you need.

74

Pay-per-visit marketplace connecting patients with licensed providers — no subscriptions, transparent per-visit pricing.

Visit Sesame Care
75

Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

Visit Twentyeight Health

Score Breakdown

DimensionSesame CareTwentyeight Health
Overall Score74/10075/100 ✓
Trust & Safety30%75/10076/100 ✓
Value25%80/10080/100
Experience20%70/10072/100 ✓
Product Range15%70/10072/100 ✓
Reputation10%70/10070/100

At a Glance

Founded20192018
HeadquartersNew York, NYBrooklyn, NY
Publicly tradedNoNo
Treatment categories64
Treatments listed77
Starting price$11/mo$15/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategorySesame CareTwentyeight Health
Women's Health—$15–$19.99
Complete Care Membership
Dermatology——
Weight Loss / GLP-1$59–$99
Weight Loss Program (subscription)
—

Sesame Care

+No subscription required — pay-per-visit model
+Transparent pricing shown before booking
+Wide range of specialties available
−No integrated pharmacy
−Less continuity of care than subscriptions
−Provider quality varies in marketplace model
Read the full Sesame Care review →

Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance
+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do
+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours
−Medications are billed separately from the membership, which some reviewers say caused unexpected charges
−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states
−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems
Read the full Twentyeight Health review →

Sesame Care vs Twentyeight Health — FAQ

Is Sesame Care better than Twentyeight Health?

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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 74/100), leading on trust & safety, experience, product range. Sesame Care has the lower entry price (from $11/mo vs $15/mo), so the better value depends on which treatment you need.

Is Sesame Care or Twentyeight Health cheaper?

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Sesame Care has the lower starting price (from $11/mo vs $15/mo for Twentyeight Health). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Sesame Care and Twentyeight Health both offer?

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Both platforms treat Women's Health, Dermatology, Weight Loss / GLP-1. Sesame Care covers 6 treatment categories total and Twentyeight Health covers 4.

Still deciding?

Sesame Care alternativesTwentyeight Health alternativesTake the Match Quiz