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Shed vs Twentyeight Health: Which Is Better?

Head-to-head comparison of Shed and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 67/100), leading on trust & safety, value, experience, reputation.

67
Shed
Good

Weight loss, hair loss, and longevity telehealth with multiple GLP-1 delivery formats including drops, lozenges, and oral tablets.

Visit Shed
75

Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

Visit Twentyeight Health

Score Breakdown

DimensionShedTwentyeight Health
Overall Score67/10075/100 ✓
Trust & Safety30%60/10076/100 ✓
Value25%70/10080/100 ✓
Experience20%70/10072/100 ✓
Product Range15%72/10072/100
Reputation10%62/10070/100 ✓

At a Glance

Founded20222018
HeadquartersGilbert, AZBrooklyn, NY
Publicly tradedNoNo
Treatment categories34
Treatments listed137
Starting price$43/mo$15/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryShedTwentyeight Health
Weight Loss / GLP-1$115
Naltrexone + Bupropion Capsules
—

Shed

+Widest variety of GLP-1 delivery formats: injections, drops, lozenges, and oral tablets
+Both compounded and brand-name GLP-1 options (Wegovy, Zepbound) available
+10% body weight loss guarantee or money back
−Two-month minimum commitment before cancellation allowed
−Cash-pay only — no insurance accepted
−BBB rating 2.87/5 (not accredited) with billing and cancellation complaints
Read the full Shed review →

Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance
+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do
+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours
−Medications are billed separately from the membership, which some reviewers say caused unexpected charges
−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states
−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems
Read the full Twentyeight Health review →

Shed vs Twentyeight Health — FAQ

Is Shed better than Twentyeight Health?

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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 67/100), leading on trust & safety, value, experience, reputation.

Is Shed or Twentyeight Health cheaper?

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Twentyeight Health has the lower starting price (from $15/mo vs $43/mo for Shed). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Shed and Twentyeight Health both offer?

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Both platforms treat Weight Loss / GLP-1. Shed covers 3 treatment categories total and Twentyeight Health covers 4.

Still deciding?

Shed alternativesTwentyeight Health alternativesTake the Match Quiz