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Sprout Health vs Twentyeight Health: Which Is Better?

Head-to-head comparison of Sprout Health and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 50.9/100), leading on trust & safety, value, experience, product range, reputation.

51
Sprout Health
Below Average

Sprout Health is an Encinitas, CA telehealth brand selling compounded semaglutide, tirzepatide and NAD+. It received an FDA warning letter in September 2025 and has an F rating from the BBB.

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75

Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

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Score Breakdown

DimensionSprout HealthTwentyeight Health
Overall Score50.9/10075/100 ✓
Trust & Safety30%45/10076/100 ✓
Value25%62/10080/100 ✓
Experience20%48/10072/100 ✓
Product Range15%55/10072/100 ✓
Reputation10%40/10070/100 ✓

At a Glance

Founded20212018
HeadquartersEncinitas, CABrooklyn, NY
Publicly tradedNoNo
Treatment categories24
Treatments listed57
Starting price$149/mo$15/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategorySprout HealthTwentyeight Health
Weight Loss / GLP-1$149–$249
Compounded Semaglutide
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Sprout Health

+Offers both compounded (semaglutide, tirzepatide) and branded (Wegovy, Zepbound) GLP-1s alongside NAD+
+Entry pricing ($149/mo semaglutide, $199/mo tirzepatide) is published before intake
+Prescribing runs through MD Integrations, an established white-label physician network
−FDA warning letter (Sept 9, 2025) for marketing compounded GLP-1s as 'FDA-approved'
−BBB rating of F for failing to respond to complaints; multiple reports of patients forced to use chargebacks or stop-payments to cancel
−Recurring complaints of late or missing refills, wrong doses shipped, and no phone support
Read the full Sprout Health review →

Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance
+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do
+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours
−Medications are billed separately from the membership, which some reviewers say caused unexpected charges
−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states
−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems
Read the full Twentyeight Health review →

Sprout Health vs Twentyeight Health — FAQ

Is Sprout Health better than Twentyeight Health?

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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 50.9/100), leading on trust & safety, value, experience, product range, reputation.

Is Sprout Health or Twentyeight Health cheaper?

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Twentyeight Health has the lower starting price (from $15/mo vs $149/mo for Sprout Health). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Sprout Health and Twentyeight Health both offer?

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Both platforms treat Weight Loss / GLP-1. Sprout Health covers 2 treatment categories total and Twentyeight Health covers 4.

Still deciding?

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