Home›Compare›Syra Rx vs Twentyeight Health

Syra Rx vs Twentyeight Health: Which Is Better?

Head-to-head comparison of Syra Rx and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 53.5/100), leading on trust & safety, value, experience, product range, reputation.

54
Syra Rx
Below Average

Syra Rx is a 2026-launched, affiliate-distributed telehealth storefront for compounded GLP-1s, NAD+, sermorelin, tesamorelin and ED treatment, with clinical care outsourced to LocumTele and fulfillment by Rush Pharmacy.

Visit Syra Rx
75

Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

Visit Twentyeight Health

Score Breakdown

DimensionSyra RxTwentyeight Health
Overall Score53.5/10075/100 ✓
Trust & Safety30%50/10076/100 ✓
Value25%56/10080/100 ✓
Experience20%50/10072/100 ✓
Product Range15%70/10072/100 ✓
Reputation10%40/10070/100 ✓

At a Glance

Founded20262018
Headquarters—Brooklyn, NY
Publicly tradedNoNo
Treatment categories34
Treatments listed57
Starting price$30/mo$15/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategorySyra RxTwentyeight Health
Weight Loss / GLP-1$199–$399
Compounded GLP-1 (semaglutide/tirzepatide)
—
Sexual Health$30–$100
ED Treatment
—

Syra Rx

+Discloses its provider network (LocumTele) and dispensing pharmacy (Rush Pharmacy) by name in the FAQ
+One of few consumer brands offering tesamorelin alongside sermorelin and NAD+
+States a fast fulfillment window (usually 1–2 business days after approval)
−No prices published anywhere on the site; costs appear only inside third-party intake funnels
−Launched in 2026 with no independent patient reviews and no physical address disclosed
−Terms of service cover only GLP-1 services even though the site markets peptides, NAD+ and ED treatment
Read the full Syra Rx review →

Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance
+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do
+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours
−Medications are billed separately from the membership, which some reviewers say caused unexpected charges
−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states
−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems
Read the full Twentyeight Health review →

Syra Rx vs Twentyeight Health — FAQ

Is Syra Rx better than Twentyeight Health?

▾

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 53.5/100), leading on trust & safety, value, experience, product range, reputation.

Is Syra Rx or Twentyeight Health cheaper?

▾

Twentyeight Health has the lower starting price (from $15/mo vs $30/mo for Syra Rx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Syra Rx and Twentyeight Health both offer?

▾

Both platforms treat Weight Loss / GLP-1, Sexual Health. Syra Rx covers 3 treatment categories total and Twentyeight Health covers 4.

Still deciding?

Syra Rx alternativesTwentyeight Health alternativesTake the Match Quiz