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System Labs vs Yucca Health: Which Is Better?

Head-to-head comparison of System Labs and Yucca Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Yucca Health scores higher overall in our independent evaluation (68.3/100 vs 56.4/100), leading on trust & safety, value, experience, product range, reputation. System Labs has the lower entry price (from $89/mo vs $125/mo), so the better value depends on which treatment you need.

56

System Labs is a San Francisco-based telehealth service prescribing compounded NAD+, sermorelin, glutathione and MIC-B12, with half-price first months.

Visit System Labs
68

Yucca Health is a Beverly Hills-based telehealth platform selling compounded semaglutide and tirzepatide at flat, dose-independent prices, plus compounded NAD+ and sermorelin.

Visit Yucca Health

Score Breakdown

DimensionSystem LabsYucca Health
Overall Score56.4/10068.3/100 ✓
Trust & Safety30%52/10064/100 ✓
Value25%68/10080/100 ✓
Experience20%55/10072/100 ✓
Product Range15%55/10058/100 ✓
Reputation10%45/10060/100 ✓

At a Glance

Founded—2025
HeadquartersSan Francisco, CABeverly Hills, CA
Publicly tradedNoNo
Treatment categories12
Treatments listed64
Starting price$89/mo$125/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategorySystem LabsYucca Health
Longevity & Peptides$89
MIC+B12 Injection
$158–$215
NAD+ Injection

System Labs

+Every price is posted on the site, including a first-month discount of roughly 40–50%
+Names its main compounding pharmacy (The Pharmacy Hub, Miami) and three board-certified physician advisors
+Both injectable and non-injectable options (NAD+ nasal spray, oral sermorelin)
−Trustpilot removed its business profile for guideline violations, so there is no independent review base
−'20k+ patients' claim is unverified; founding date and company history are not disclosed
−All sales are final once shipped; terms impose binding arbitration and a class-action waiver
Read the full System Labs review →

Yucca Health

+Full price grid published before intake: semaglutide $146/mo monthly, $140/mo quarterly or $125/mo on a 6-month prepay; tirzepatide $258, $248 or $225/mo
+Locked pricing covers the whole dose range, so titrating up does not raise the bill; pausing keeps the locked rate
+No separate membership or consultation fee; plans include the provider consult, medication, injection supplies and free 2-day shipping
−Dispensing pharmacies are not named on the public site; they appear only in the patient portal and on the label after ordering
−BBB rating of C+ (not accredited) with five closed complaints; one Trustpilot reviewer reports prepaying six months and receiving three
−About 6% of roughly 1,230 Trustpilot reviews are 1-star, citing lack of results after months of treatment and refund disputes
Read the full Yucca Health review →

System Labs vs Yucca Health — FAQ

Is System Labs better than Yucca Health?

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Yucca Health scores higher overall in our independent evaluation (68.3/100 vs 56.4/100), leading on trust & safety, value, experience, product range, reputation. System Labs has the lower entry price (from $89/mo vs $125/mo), so the better value depends on which treatment you need.

Is System Labs or Yucca Health cheaper?

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System Labs has the lower starting price (from $89/mo vs $125/mo for Yucca Health). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do System Labs and Yucca Health both offer?

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Both platforms treat Longevity & Peptides. System Labs covers 1 treatment category total and Yucca Health covers 2.

Still deciding?

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