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Twentyeight Health vs XYON Health: Which Is Better?

Head-to-head comparison of Twentyeight Health and XYON Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 65.9/100), leading on trust & safety, value, experience, product range.

75

Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

Visit Twentyeight Health
66

Physician-led hair loss telehealth brand co-founded by hair transplant surgeons, specializing in topical finasteride and combination scalp formulas.

Visit XYON Health

Score Breakdown

DimensionTwentyeight HealthXYON Health
Overall Score75/100 ✓65.9/100
Trust & Safety30%76/100 ✓68/100
Value25%80/100 ✓62/100
Experience20%72/100 ✓64/100
Product Range15%72/100 ✓68/100
Reputation10%70/10070/100

At a Glance

Founded20182019
HeadquartersBrooklyn, NYVancouver, BC, Canada
Publicly tradedNoNo
Treatment categories43
Treatments listed73
Starting price$15/mo$109/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryTwentyeight HealthXYON Health
Women's Health$15–$19.99
Complete Care Membership
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Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance
+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do
+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours
−Medications are billed separately from the membership, which some reviewers say caused unexpected charges
−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states
−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems
Read the full Twentyeight Health review →

XYON Health

+Co-founded by established hair transplant surgeons, lending clinical credibility to formulation choices
+One of the most-discussed topical finasteride brands in the r/tressless community
+Broad hair-loss formulation range: topical finasteride, topical dutasteride, combination gel, and oral options
−Small Trustpilot sample (65 reviews) limits confidence in the 3.7/5 rating
−Topical gel texture ('sticky,' hard to apply) is a recurring patient complaint
−No live communication channel with prescribing clinicians reported by several patients
Read the full XYON Health review →

Twentyeight Health vs XYON Health — FAQ

Is Twentyeight Health better than XYON Health?

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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 65.9/100), leading on trust & safety, value, experience, product range.

Is Twentyeight Health or XYON Health cheaper?

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Twentyeight Health has the lower starting price (from $15/mo vs $109/mo for XYON Health). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Twentyeight Health and XYON Health both offer?

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Both platforms treat Women's Health. Twentyeight Health covers 4 treatment categories total and XYON Health covers 3.

Still deciding?

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