HomeWeight Loss / GLP-1Tirzepatide

Tirzepatide Online

Brand names: Mounjaro, Zepbound

Tirzepatide is a dual GIP/GLP-1 receptor agonist made by Eli Lilly. It targets two gut hormones instead of one, and in clinical trials showed even greater weight loss than semaglutide — up to 22.5% of body weight. It's available as Mounjaro (for diabetes) and Zepbound (for weight loss).

13 providers on TelehealthMatchFrom $79/mo*Full cost breakdown →

How Tirzepatide Works

Tirzepatide activates both GIP and GLP-1 receptors — two separate hormones involved in appetite regulation, blood sugar control, and fat metabolism. This dual action is believed to produce greater effects than targeting GLP-1 alone. It slows digestion, reduces hunger, and improves how the body processes insulin and stores fat.

What to Expect

Appetite suppression typically begins within 1-2 weeks. Weight loss of 5%+ body weight is common by month 3. In the SURMOUNT trials, average weight loss was 22.5% at 72 weeks on the highest dose. Dose escalation follows a similar gradual schedule to semaglutide.

Tirzepatide Pricing Comparison

Sorted by lowest starting price.

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

ProviderScoreProductPrice/moIncludes
Noom
60
Noom GLP-1Rx Plus (Compounded Tirzepatide)$149–$299
$149 first 4-week supply
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Noom Microdose GLP-1Rx Plus (Tirzepatide)$79–$199
$79 first 4-week supply
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Ivim Health
58
Compounded Tirzepatide (12-month plan)$208
First month membership free
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Shed
67
Compounded Tirzepatide (injectable)$239–$299
$239/mo on 12-month plan, $269/mo on 6-month
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Fridays
55
Compounded Tirzepatide$240–$359
$100 off any plan via codes; up to 50% off first order
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Brand-name Zepbound$1828
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Mochi Health
67
Compounded Tirzepatide (All Doses)$278
$39 first month membership (vs $79); current promo: med $90/mo (reg. $199)
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MEDVi
71
Compounded Tirzepatide (Injectable)$349–$499
$349 first month
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Compounded Tirzepatide (Oral)$279
$279 first month
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Eden
64
Compounded Tirzepatide$298
First month $238 ($199 med + $39 membership)
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Ro
77
Branded Zepbound (Vials & KwikPen)$299–$449
$39 first month membership; then $149/mo (prepay plans from $74/mo)
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Direct Meds
74
Compounded Tirzepatide (injectable)$399
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Compounded Tirzepatide (sublingual)$299
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TrimRx
52
Compounded Tirzepatide (Injectable)$349–$449
$349 first month (reg. $449 after)
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Compounded Tirzepatide (Oral)$330–$399
$330 first month (reg. $399 after)
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Brand-name Zepbound$1399
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LifeMD
68
Branded Zepbound Vials (tirzepatide)$349–$499
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Hims & Hers
78
Branded Zepbound (tirzepatide)$399
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Remedy Meds
69
Compounded Tirzepatide$399
$279 first month (save $120); price-lock guarantee
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Common Side Effects

  • Nausea (especially during dose increases)
  • Diarrhea
  • Constipation
  • Decreased appetite
  • Abdominal pain
  • Vomiting
  • Injection site reactions

Serious Side Effects

  • !Pancreatitis
  • !Gallbladder disease
  • !Hypoglycemia (especially with insulin or sulfonylureas)
  • !Kidney problems from dehydration
  • !Thyroid C-cell tumors (animal studies — risk to humans uncertain)
  • !Severe allergic reactions (rare)

Tirzepatide Is Not For

  • People with personal or family history of medullary thyroid carcinoma
  • People with MEN 2 syndrome
  • Pregnant or breastfeeding women
  • People with severe gastrointestinal disease

Tirzepatide — Frequently Asked Questions

What is the difference between tirzepatide and semaglutide?

Both are injectable weight loss medications, but tirzepatide targets two hormones (GIP + GLP-1) while semaglutide targets only GLP-1. Clinical trials showed tirzepatide produced greater average weight loss (22.5% vs 15-17%). Tirzepatide is made by Eli Lilly; semaglutide by Novo Nordisk.

How much does tirzepatide cost through telehealth?

Compounded tirzepatide through telehealth typically runs $199-599/month. Brand-name Zepbound costs $1,000+/month without insurance, though Ro has a direct Eli Lilly partnership offering negotiated pricing.

Is Mounjaro the same as Zepbound?

They are the same molecule (tirzepatide) made by Eli Lilly, but Mounjaro is FDA-approved for type 2 diabetes and Zepbound is approved specifically for weight loss. The dosing and medication are identical.

Can I switch from semaglutide to tirzepatide?

Yes, switching is common and should be done under medical guidance. Your telehealth provider will typically start you at a lower dose of tirzepatide and escalate gradually, similar to initial treatment. Some patients switch because they plateau on semaglutide or want greater weight loss.

Medical disclaimer: The information on this page is for educational purposes only and is not medical advice.Tirzepatide requires a prescription from a licensed healthcare provider. Side effects, risks, and suitability vary by individual. Always consult your doctor before starting, stopping, or changing any medication. TelehealthMatch is not a healthcare provider.

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