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AgelessRx vs Enhance.MD: Which Is Better?

Head-to-head comparison of AgelessRx and Enhance.MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

AgelessRx scores higher overall in our independent evaluation (73.4/100 vs 66.9/100), leading on value, experience, product range, reputation. Enhance.MD comes out ahead on trust & safety.

73

AgelessRx is an Ann Arbor-based longevity telehealth company that prescribes rapamycin, metformin, low-dose naltrexone and NAD+, and also sells compounded and branded GLP-1s.

Visit AgelessRx
67

Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

Visit Enhance.MD

Score Breakdown

DimensionAgelessRxEnhance.MD
Overall Score73.4/100 ✓66.9/100
Trust & Safety30%72/10076/100 ✓
Value25%74/100 ✓60/100
Experience20%70/100 ✓68/100
Product Range15%82/100 ✓60/100
Reputation10%70/100 ✓65/100

At a Glance

Founded20192019
HeadquartersAnn Arbor, MISan Diego, CA
Publicly tradedNoNo
Treatment categories42
Treatments listed145
Starting price$25/mo$169/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryAgelessRxEnhance.MD
Longevity & Peptides$25
Metformin
$169
NAD+ Therapy
Weight Loss / GLP-1$99
Microdosing Semaglutide
$169
Microdose Tirzepatide

AgelessRx

+Deepest longevity formulary we track: rapamycin ($65/mo), metformin and LDN ($25/mo), NAD+, sermorelin, glutathione and B12
+Research-led: publishes a named medical director and runs its own decentralised trials (e.g. PEARL rapamycin study)
+Low entry prices with video visits and shipping included and no separate membership fee
−No consolidated price list; GLP-1 and NAD+ prices vary widely by plan length ($79 vs $235/mo reported for NAD+ injections)
−Headline microdosed tirzepatide price ($159/mo) requires a four-month plan billed upfront (~$636)
−Reviewers report slow support replies, billing/card-decline errors and heavy marketing email
Read the full AgelessRx review →

Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

AgelessRx vs Enhance.MD — FAQ

Is AgelessRx better than Enhance.MD?

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AgelessRx scores higher overall in our independent evaluation (73.4/100 vs 66.9/100), leading on value, experience, product range, reputation. Enhance.MD comes out ahead on trust & safety.

Is AgelessRx or Enhance.MD cheaper?

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AgelessRx has the lower starting price (from $25/mo vs $169/mo for Enhance.MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do AgelessRx and Enhance.MD both offer?

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Both platforms treat Longevity & Peptides, Weight Loss / GLP-1. AgelessRx covers 4 treatment categories total and Enhance.MD covers 2.

Still deciding?

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