Enhance.MD
Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.
Our Verdict
Enhance.MD scores 66.9/100 in our independent evaluation — good overall, standing out most for trust & safety. Plans start at $169/mo.
What we like
What to watch
Full Review
Established in 2019 and led by Chloe Belle Hooton, Enhance.MD (Enhance.MD LLC, with care delivered by Enhance Wellness PC and iThriveMD PC under medical director Dr. Erik Stark) runs a more clinically structured program than most cash-pay GLP-1 brands: Quest labs (CMP, lipids, TSH, HbA1c) before prescribing and every six months, video consultations, and ID verification. Pricing is flat across doses but billed every 28 days: $212 for compounded semaglutide, $280 for tirzepatide and $322 for a semaglutide-tirzepatide combination (each $100 less for the first month), plus a $169/mo tirzepatide microdose and $169/mo NAD+. It names its fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub) and holds a BBB A+ rating, while its Trustpilot rating is a more modest 4.0/5 on 161 reviews, with complaints about delayed or cancelled shipments and pharmacy switches. It does not currently serve AL, AR, GA, HI, LA, MS, MO, ND, SC or TN.
Last researched: 2026-09-25
Enhance.MD GLP-1 pricing: month 1 vs. month 2+
The advertised price is often only the first month. This is what each plan costs once intro pricing ends.
All-in prices: medication plus any required membership. Verified 2026-08-17. Model your own year →
| Plan | Month 1 | Month 2+ | Year one | What to know |
|---|---|---|---|---|
| GLP-1 Core (compounded semaglutide) Compounded | $112 | $212/4 wk | $2,656 | +$100 after month 1Same price at every doseBilled every 4 weeks (13×/yr)Labs included Renews every 28 days (13 charges/yr); labs every 6 months included |
| GLP-1 Advanced (compounded tirzepatide) Compounded | $180 | $280/4 wk | $3,540 | +$100 after month 1Same price at every doseBilled every 4 weeks (13×/yr)Labs included Renews every 28 days (13 charges/yr); labs every 6 months included |
| Microdose Tirzepatide Compounded | $169 | $169/mo | $2,028 | No price jump after month 1Same price at every dose Capped at 1mg/week; medication ships every 12 weeks |
Pricing
Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.
| Treatment | Category | Price/mo | Includes | Notes |
|---|---|---|---|---|
| GLP-1 Core (compounded semaglutide) | Weight Loss / GLP-1 | $212 | ● Consults● Lab work● Shipping | $112 first month Subscription required |
| GLP-1 Advanced (compounded tirzepatide) | Weight Loss / GLP-1 | $280 | ● Consults● Lab work● Shipping | $180 first month Subscription required |
| GLP-1 Elite (semaglutide + tirzepatide) | Weight Loss / GLP-1 | $322 | ● Consults● Lab work● Shipping | $222 first month Subscription required |
| Microdose Tirzepatide | Weight Loss / GLP-1 | $169 | ● Consults○ Lab work● Shipping | Subscription required |
| NAD+ Therapy | Weight Loss / GLP-1 | $169 | ● Consults○ Lab work● Shipping | Subscription required |
Score Breakdown
How Enhance.MD Stacks Up
Enhance.MD — Frequently Asked Questions
Is Enhance.MD legit?
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We rate Enhance.MD's trust & safety at 76/100 (very good), based on FDA compliance, licensing, and pricing transparency. Its overall score across all five of our scoring dimensions is 66.9/100 — see the full breakdown above.
How much does Enhance.MD cost?
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Enhance.MD's plans start at $169/mo. Exact pricing varies by treatment — see the pricing table above for a breakdown by product. Prices were last verified 2026-09-25.
Does Enhance.MD require a subscription?
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Yes — every Enhance.MD plan we track requires an ongoing subscription.
What does Enhance.MD treat?
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Enhance.MD offers treatment in: Weight Loss / GLP-1, Longevity & Peptides.