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AgelessRx vs Niagen Plus: Which Is Better?

Head-to-head comparison of AgelessRx and Niagen Plus based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

AgelessRx scores higher overall in our independent evaluation (73.4/100 vs 64.7/100), leading on value, experience, product range, reputation. Niagen Plus comes out ahead on trust & safety.

73

AgelessRx is an Ann Arbor-based longevity telehealth company that prescribes rapamycin, metformin, low-dose naltrexone and NAD+, and also sells compounded and branded GLP-1s.

Visit AgelessRx
65

Prescription-only telehealth program from Nasdaq-listed Niagen Bioscience (formerly ChromaDex) selling an at-home injection kit of nicotinamide riboside (NR), an NAD+ precursor, rather than NAD+ itself.

Visit Niagen Plus

Score Breakdown

DimensionAgelessRxNiagen Plus
Overall Score73.4/100 ✓64.7/100
Trust & Safety30%72/10078/100 ✓
Value25%74/100 ✓70/100
Experience20%70/100 ✓58/100
Product Range15%82/100 ✓36/100
Reputation10%70/100 ✓68/100

At a Glance

Founded20192024
HeadquartersAnn Arbor, MILos Angeles, CA
Publicly tradedNoYes (NAGE)
Treatment categories41
Treatments listed141
Starting price$25/mo$149/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryAgelessRxNiagen Plus
Longevity & Peptides$25
Metformin
$149
Niagen At-Home Injection Kit (NR chloride 500 mg, ~28 days)

AgelessRx

+Deepest longevity formulary we track: rapamycin ($65/mo), metformin and LDN ($25/mo), NAD+, sermorelin, glutathione and B12
+Research-led: publishes a named medical director and runs its own decentralised trials (e.g. PEARL rapamycin study)
+Low entry prices with video visits and shipping included and no separate membership fee
−No consolidated price list; GLP-1 and NAD+ prices vary widely by plan length ($79 vs $235/mo reported for NAD+ injections)
−Headline microdosed tirzepatide price ($159/mo) requires a four-month plan billed upfront (~$636)
−Reviewers report slow support replies, billing/card-decline errors and heavy marketing email
Read the full AgelessRx review →

Niagen Plus

+Backed by a public company with 25+ years of NAD+-precursor research; it holds the patent on the active ingredient (Niagen NRCl)
+Compounded by a 503B outsourcing facility (FDA-registered, cGMP) rather than a patient-specific 503A lab alone
+Flat, published $149 kit price includes the provider consult, a ~28-day supply, supplies and free Next Day Air shipping
−Only one product, and it is NR (an NAD+ precursor), not NAD+; the studies comparing it with NAD+ IV are small and company-sponsored
−The kit showed 'more stock coming soon' at the time of research, so availability is not reliable
−The site does not name the telehealth medical group or the dispensing 503A pharmacy
Read the full Niagen Plus review →

AgelessRx vs Niagen Plus — FAQ

Is AgelessRx better than Niagen Plus?

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AgelessRx scores higher overall in our independent evaluation (73.4/100 vs 64.7/100), leading on value, experience, product range, reputation. Niagen Plus comes out ahead on trust & safety.

Is AgelessRx or Niagen Plus cheaper?

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AgelessRx has the lower starting price (from $25/mo vs $149/mo for Niagen Plus). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do AgelessRx and Niagen Plus both offer?

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Both platforms treat Longevity & Peptides. AgelessRx covers 4 treatment categories total and Niagen Plus covers 1.

Still deciding?

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