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65
Fair

Niagen Plus

NAGE

Prescription-only telehealth program from Nasdaq-listed Niagen Bioscience (formerly ChromaDex) selling an at-home injection kit of nicotinamide riboside (NR), an NAD+ precursor, rather than NAD+ itself.

Los Angeles, CAFounded 2024100-200 employeesReviewed 2026-09-24
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Our Verdict

Niagen Plus scores 64.7/100 in our independent evaluation — fair overall, standing out most for trust & safety. Plans start at $149/mo.

What we like

+Backed by a public company with 25+ years of NAD+-precursor research; it holds the patent on the active ingredient (Niagen NRCl)
+Compounded by a 503B outsourcing facility (FDA-registered, cGMP) rather than a patient-specific 503A lab alone
+Flat, published $149 kit price includes the provider consult, a ~28-day supply, supplies and free Next Day Air shipping
+Subcutaneous NR injections take seconds at home, versus multi-hour NAD+ IV drips

What to watch

−Only one product, and it is NR (an NAD+ precursor), not NAD+; the studies comparing it with NAD+ IV are small and company-sponsored
−The kit showed 'more stock coming soon' at the time of research, so availability is not reliable
−The site does not name the telehealth medical group or the dispensing 503A pharmacy
−Parent Niagen Bioscience faces a June 2026 class action alleging Tru Niagen is falsely marketed as 'clinically proven'
−Not available to ship to Alabama, Arkansas, California or Massachusetts

Full Review

Niagen Plus is the clinical arm of Niagen Bioscience (NASDAQ: NAGE; formerly ChromaDex, maker of Tru Niagen). The company says 1,200+ clinics give Niagen IV and IM infusions, and it launched a direct-to-patient telehealth program on May 4, 2026. The at-home kit costs $149, which includes a $20 provider consult: a 500 mg vial of patented nicotinamide riboside chloride (NRCl) with bacteriostatic water and syringes, for subcutaneous doses every 3-5 days over about 28 days. NR is an NAD+ precursor, not NAD+, and the company cites shorter infusion times and fewer side effects than NAD+ IV, based on a 2024 preprint and a 2026 retrospective study it sponsored. A 503B outsourcing facility compounds the kit and a 503A pharmacy ships it. The site does not name the telehealth medical group. At the time of research the kit page said 'more stock coming soon', and the kit does not ship to AL, AR, CA or MA. The parent faces a June 2026 consumer class action alleging its Tru Niagen supplement is falsely marketed as 'clinically proven'.

Last researched: 2026-09-24

Pricing

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

TreatmentCategoryPrice/moIncludesNotes
Niagen At-Home Injection Kit (NR chloride 500 mg, ~28 days)Longevity & Peptides$149
● Consults○ Lab work● Shipping
No subscription needed

Score Breakdown

78
Trust & Safety (30%)
70
Value (25%)
58
Experience (20%)
36
Product Range (15%)
68
Reputation (10%)
Trust & Safety78/100
Value70/100
Experience58/100
Product Range36/100
Reputation68/100

Niagen Plus — Frequently Asked Questions

Is Niagen Plus legit?

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We rate Niagen Plus's trust & safety at 78/100 (very good), based on FDA compliance, licensing, and pricing transparency. Its overall score across all five of our scoring dimensions is 64.7/100 — see the full breakdown above.

How much does Niagen Plus cost?

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Niagen Plus's plans start at $149/mo. Exact pricing varies by treatment — see the pricing table above for a breakdown by product. Prices were last verified 2026-09-24.

Does Niagen Plus require a subscription?

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No — none of the Niagen Plus plans we track require a subscription.

What does Niagen Plus treat?

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Niagen Plus offers treatment in: Longevity & Peptides.