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AlphaMD vs Defy Medical: Which Is Better?

Head-to-head comparison of AlphaMD and Defy Medical based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 64.6/100), leading on trust & safety, experience, product range, reputation. AlphaMD comes out ahead on value. AlphaMD has the lower entry price (from $50/mo vs $150/mo), so the better value depends on which treatment you need.

65

AlphaMD is a small Washington-based TRT platform with published, commitment-tiered pricing from $98/mo, plus HCG, enclomiphene, female TRT, sermorelin, and NAD+.

Visit AlphaMD
72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical

Score Breakdown

DimensionAlphaMDDefy Medical
Overall Score64.6/10071.9/100 ✓
Trust & Safety30%66/10072/100 ✓
Value25%72/100 ✓60/100
Experience20%60/10078/100 ✓
Product Range15%60/10078/100 ✓
Reputation10%58/10080/100 ✓

At a Glance

Founded—2011
HeadquartersLynnwood, WATampa, FL
Publicly tradedNoNo
Treatment categories43
Treatments listed64
Starting price$50/mo$150/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryAlphaMDDefy Medical
Hormone Therapy$50
At-Home Testosterone Test
$150–$250
Women's Bioidentical HRT

AlphaMD

+Published TRT pricing with medication and supplies included: $98/mo annual, $109/mo semi-annual, $129/mo on a 3-month commitment
+20% discount for active military, veterans, and first responders
+Names its compounding pharmacy (AnazaoHealth, Tampa) and starts patients with a free at-home hormone test kit
−Every TRT plan carries a minimum commitment of at least 3 months
−Small review base (52 Trustpilot reviews), with complaints about unreturned calls and onboarding taking over a month
−Narrow catalog centered on testosterone; no weight-loss, hair-loss, or standalone ED program is published
Read the full AlphaMD review →

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

AlphaMD vs Defy Medical — FAQ

Is AlphaMD better than Defy Medical?

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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 64.6/100), leading on trust & safety, experience, product range, reputation. AlphaMD comes out ahead on value. AlphaMD has the lower entry price (from $50/mo vs $150/mo), so the better value depends on which treatment you need.

Is AlphaMD or Defy Medical cheaper?

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AlphaMD has the lower starting price (from $50/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do AlphaMD and Defy Medical both offer?

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Both platforms treat Hormone Therapy. AlphaMD covers 4 treatment categories total and Defy Medical covers 3.

Still deciding?

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