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AlphaMD vs Niagen Plus: Which Is Better?

Head-to-head comparison of AlphaMD and Niagen Plus based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Niagen Plus scores higher overall in our independent evaluation (64.7/100 vs 64.6/100), leading on trust & safety, reputation. AlphaMD comes out ahead on value, experience, product range. AlphaMD has the lower entry price (from $50/mo vs $149/mo), so the better value depends on which treatment you need.

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AlphaMD is a small Washington-based TRT platform with published, commitment-tiered pricing from $98/mo, plus HCG, enclomiphene, female TRT, sermorelin, and NAD+.

Visit AlphaMD
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Prescription-only telehealth program from Nasdaq-listed Niagen Bioscience (formerly ChromaDex) selling an at-home injection kit of nicotinamide riboside (NR), an NAD+ precursor, rather than NAD+ itself.

Visit Niagen Plus

Score Breakdown

DimensionAlphaMDNiagen Plus
Overall Score64.6/10064.7/100 ✓
Trust & Safety30%66/10078/100 ✓
Value25%72/100 ✓70/100
Experience20%60/100 ✓58/100
Product Range15%60/100 ✓36/100
Reputation10%58/10068/100 ✓

At a Glance

Founded—2024
HeadquartersLynnwood, WALos Angeles, CA
Publicly tradedNoYes (NAGE)
Treatment categories41
Treatments listed61
Starting price$50/mo$149/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryAlphaMDNiagen Plus
Longevity & Peptides$130
NAD+ Injections (90-day supply)
$149
Niagen At-Home Injection Kit (NR chloride 500 mg, ~28 days)

AlphaMD

+Published TRT pricing with medication and supplies included: $98/mo annual, $109/mo semi-annual, $129/mo on a 3-month commitment
+20% discount for active military, veterans, and first responders
+Names its compounding pharmacy (AnazaoHealth, Tampa) and starts patients with a free at-home hormone test kit
−Every TRT plan carries a minimum commitment of at least 3 months
−Small review base (52 Trustpilot reviews), with complaints about unreturned calls and onboarding taking over a month
−Narrow catalog centered on testosterone; no weight-loss, hair-loss, or standalone ED program is published
Read the full AlphaMD review →

Niagen Plus

+Backed by a public company with 25+ years of NAD+-precursor research; it holds the patent on the active ingredient (Niagen NRCl)
+Compounded by a 503B outsourcing facility (FDA-registered, cGMP) rather than a patient-specific 503A lab alone
+Flat, published $149 kit price includes the provider consult, a ~28-day supply, supplies and free Next Day Air shipping
−Only one product, and it is NR (an NAD+ precursor), not NAD+; the studies comparing it with NAD+ IV are small and company-sponsored
−The kit showed 'more stock coming soon' at the time of research, so availability is not reliable
−The site does not name the telehealth medical group or the dispensing 503A pharmacy
Read the full Niagen Plus review →

AlphaMD vs Niagen Plus — FAQ

Is AlphaMD better than Niagen Plus?

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Niagen Plus scores higher overall in our independent evaluation (64.7/100 vs 64.6/100), leading on trust & safety, reputation. AlphaMD comes out ahead on value, experience, product range. AlphaMD has the lower entry price (from $50/mo vs $149/mo), so the better value depends on which treatment you need.

Is AlphaMD or Niagen Plus cheaper?

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AlphaMD has the lower starting price (from $50/mo vs $149/mo for Niagen Plus). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do AlphaMD and Niagen Plus both offer?

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Both platforms treat Longevity & Peptides. AlphaMD covers 4 treatment categories total and Niagen Plus covers 1.

Still deciding?

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