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AlphaMD vs Synergy Rx: Which Is Better?

Head-to-head comparison of AlphaMD and Synergy Rx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

AlphaMD scores higher overall in our independent evaluation (64.6/100 vs 51.9/100), leading on trust & safety, value, experience, product range, reputation.

65

AlphaMD is a small Washington-based TRT platform with published, commitment-tiered pricing from $98/mo, plus HCG, enclomiphene, female TRT, sermorelin, and NAD+.

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52
Synergy Rx
Below Average

Synergy Rx is a GLP-1 and peptide storefront launched in 2026 on CareValidate's white-label platform. It sells compounded semaglutide and tirzepatide as injections or oral tablets, prescribed through the Lion MD network.

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Score Breakdown

DimensionAlphaMDSynergy Rx
Overall Score64.6/100 ✓51.9/100
Trust & Safety30%66/100 ✓48/100
Value25%72/100 ✓60/100
Experience20%60/100 ✓50/100
Product Range15%60/100 ✓58/100
Reputation10%58/100 ✓38/100

At a Glance

Founded—2026
HeadquartersLynnwood, WA—
Publicly tradedNoNo
Treatment categories43
Treatments listed69
Starting price$50/mo$109/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryAlphaMDSynergy Rx
Longevity & Peptides$130
NAD+ Injections (90-day supply)
$109
B12 Methylcobalamin

AlphaMD

+Published TRT pricing with medication and supplies included: $98/mo annual, $109/mo semi-annual, $129/mo on a 3-month commitment
+20% discount for active military, veterans, and first responders
+Names its compounding pharmacy (AnazaoHealth, Tampa) and starts patients with a free at-home hormone test kit
−Every TRT plan carries a minimum commitment of at least 3 months
−Small review base (52 Trustpilot reviews), with complaints about unreturned calls and onboarding taking over a month
−Narrow catalog centered on testosterone; no weight-loss, hair-loss, or standalone ED program is published
Read the full AlphaMD review →

Synergy Rx

+Offers both injectable and oral-tablet compounded semaglutide and tirzepatide
+Names its four dispensing pharmacies and supervising Lion MD physicians
+Wider peptide menu than sibling storefronts: NAD+, sermorelin, glutathione, B12, PT-141
−Independent review found the intake does not screen for medullary thyroid cancer or MEN2 history (GLP-1 boxed-warning contraindication)
−Pricing is withheld until after the consult on the brand's own site; consult fee is disclosed inconsistently ($59 vs $80)
−Launched in 2026 with no Trustpilot, BBB or patient-review history
Read the full Synergy Rx review →

AlphaMD vs Synergy Rx — FAQ

Is AlphaMD better than Synergy Rx?

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AlphaMD scores higher overall in our independent evaluation (64.6/100 vs 51.9/100), leading on trust & safety, value, experience, product range, reputation.

Is AlphaMD or Synergy Rx cheaper?

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AlphaMD has the lower starting price (from $50/mo vs $109/mo for Synergy Rx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do AlphaMD and Synergy Rx both offer?

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Both platforms treat Longevity & Peptides. AlphaMD covers 4 treatment categories total and Synergy Rx covers 3.

Still deciding?

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