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altRx vs Defy Medical: Which Is Better?

Head-to-head comparison of altRx and Defy Medical based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 47.6/100), leading on trust & safety, experience, product range, reputation. altRx comes out ahead on value. altRx has the lower entry price (from $89/mo vs $150/mo), so the better value depends on which treatment you need.

48
altRx
Below Average

altRx is a Miami-operated, GLP-1-only telehealth brand advertising compounded semaglutide from $89/mo and tirzepatide from $149/mo with no separate membership fee.

Visit altRx
72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical

Score Breakdown

DimensionaltRxDefy Medical
Overall Score47.6/10071.9/100 ✓
Trust & Safety30%42/10072/100 ✓
Value25%70/100 ✓60/100
Experience20%35/10078/100 ✓
Product Range15%50/10078/100 ✓
Reputation10%30/10080/100 ✓

At a Glance

Founded—2011
HeadquartersMiami, FLTampa, FL
Publicly tradedNoNo
Treatment categories13
Treatments listed24
Starting price$89/mo$150/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryaltRxDefy Medical
Weight Loss / GLP-1$89–$159
Compounded Semaglutide (injectable)
$150–$250
GLP-1 Weight Loss (Semaglutide/Tirzepatide)

altRx

+Advertised compounded GLP-1 pricing ($89/mo semaglutide, $149/mo tirzepatide) is near the bottom of the market, with no separate membership fee
+Names its four fulfilling pharmacies (RedRock, Health Warehouse, Precision Medicine, Triad Rx) on its site
+Offers branded Wegovy, Zepbound and Ozempic prescriptions alongside compounded options
−Received an FDA warning letter (June 8, 2026) over labeling that misidentified the compounder and 'clinically proven' claims implying FDA approval
−Roughly 73-78% of Trustpilot reviews are one-star, citing undelivered refills, refused refunds, and unanswered phones and email
−Trustpilot has removed reviews on its profile for guideline breaches
Read the full altRx review →

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

altRx vs Defy Medical — FAQ

Is altRx better than Defy Medical?

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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 47.6/100), leading on trust & safety, experience, product range, reputation. altRx comes out ahead on value. altRx has the lower entry price (from $89/mo vs $150/mo), so the better value depends on which treatment you need.

Is altRx or Defy Medical cheaper?

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altRx has the lower starting price (from $89/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do altRx and Defy Medical both offer?

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Both platforms treat Weight Loss / GLP-1. altRx covers 1 treatment category total and Defy Medical covers 3.

Still deciding?

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