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Amazon One Medical vs ProlongMD: Which Is Better?

Head-to-head comparison of Amazon One Medical and ProlongMD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

ProlongMD scores higher overall in our independent evaluation (60.1/100 vs 51.1/100), leading on value, experience, product range. Amazon One Medical comes out ahead on trust & safety, reputation.

51
Amazon One Medical
Below Average

Amazon-owned virtual and in-person primary care service offering low-cost pay-per-visit and membership plans for common conditions.

Visit Amazon One Medical
60

Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

Visit ProlongMD

Score Breakdown

DimensionAmazon One MedicalProlongMD
Overall Score51.1/10060.1/100 ✓
Trust & Safety30%62/100 ✓52/100
Value25%45/10074/100 ✓
Experience20%40/10055/100 ✓
Product Range15%55/10070/100 ✓
Reputation10%50/100 ✓45/100

At a Glance

Founded20072025
HeadquartersSan Francisco, CAPhoenix, AZ
Publicly tradedNoNo
Treatment categories18
Treatments listed313
Starting price$29/mo$25/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryAmazon One MedicalProlongMD
Primary Care$29
On-Demand Messaging Visit
$79
Consultation (30-min video, credited toward treatment)

Amazon One Medical

+Backed by Amazon's infrastructure, with prescriptions routed directly to Amazon Pharmacy
+Lowest pay-per-visit pricing among mainstream primary-care telehealth options (messaging from $29, video from $49)
+Licensed physicians available 24/7 for same/next-day virtual visits across 30+ common acute conditions
−Trustpilot rating of 1.3/5 across 334 reviews, dominated by complaints of billing well above advertised prices — patients report charges of $304-$800 for visits marketed at $29-$49
−2023 FTC settlement ($5.8M) over sharing patient data with third-party ad platforms without consent
−Customer support widely described by patients as unresponsive to billing disputes
Read the full Amazon One Medical review →

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee
+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs
+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits
−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form
−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)
−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text
Read the full ProlongMD review →

Amazon One Medical vs ProlongMD — FAQ

Is Amazon One Medical better than ProlongMD?

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ProlongMD scores higher overall in our independent evaluation (60.1/100 vs 51.1/100), leading on value, experience, product range. Amazon One Medical comes out ahead on trust & safety, reputation.

Is Amazon One Medical or ProlongMD cheaper?

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ProlongMD has the lower starting price (from $25/mo vs $29/mo for Amazon One Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Amazon One Medical and ProlongMD both offer?

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Both platforms treat Primary Care. Amazon One Medical covers 1 treatment category total and ProlongMD covers 8.

Still deciding?

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