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Amble Health vs Enhance.MD: Which Is Better?

Head-to-head comparison of Amble Health and Enhance.MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Amble Health scores higher overall in our independent evaluation (68.6/100 vs 66.9/100), leading on value, experience. Enhance.MD comes out ahead on trust & safety, product range, reputation.

Amble Health is a 2023-founded compounded-GLP-1 telehealth brand offering flat, dose-independent monthly pricing for semaglutide and tirzepatide, bundled with consults and shipping.

Visit Amble Health

Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

Visit Enhance.MD

Score Breakdown

DimensionAmble HealthEnhance.MD
Overall Score68.6/100 ✓66.9/100
Trust & Safety30%68/10076/100 ✓
Value25%78/100 ✓60/100
Experience20%76/100 ✓68/100
Product Range15%50/10060/100 ✓
Reputation10%60/10065/100 ✓

At a Glance

Founded20232019
Headquarters—San Diego, CA
Publicly tradedNoNo
Treatment categories12
Treatments listed25
Starting price$135/mo$169/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryAmble HealthEnhance.MD
Weight Loss / GLP-1$135–$179
Compounded Semaglutide
$169
Microdose Tirzepatide

Amble Health

+Flat, all-in monthly pricing for compounded semaglutide and tirzepatide that doesn't change by dose, published on the website without an intake form
+Consult, medication, supplies, and shipping are all bundled into a single price with no add-on fees disclosed
+Longer-commitment discount structure rewards 6-12 month plans with the lowest per-month price ($135)
−Does not name its compounding pharmacy partner(s) publicly, unlike competitors that disclose 503A/503B sourcing
−Trustpilot complaints about medication arriving warm or thawed due to failed cold-chain packaging
−Multi-day delays reported for cancellation requests and billing dispute resolution
Read the full Amble Health review →

Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

Amble Health vs Enhance.MD — FAQ

Is Amble Health better than Enhance.MD?

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Amble Health scores higher overall in our independent evaluation (68.6/100 vs 66.9/100), leading on value, experience. Enhance.MD comes out ahead on trust & safety, product range, reputation.

Is Amble Health or Enhance.MD cheaper?

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Amble Health has the lower starting price (from $135/mo vs $169/mo for Enhance.MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Amble Health and Enhance.MD both offer?

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Both platforms treat Weight Loss / GLP-1. Amble Health covers 1 treatment category total and Enhance.MD covers 2.

Still deciding?