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Brightmeds vs Enhance.MD: Which Is Better?

Head-to-head comparison of Brightmeds and Enhance.MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Enhance.MD scores higher overall in our independent evaluation (66.9/100 vs 66.5/100), leading on trust & safety, reputation. Brightmeds comes out ahead on value, experience, product range. Brightmeds has the lower entry price (from $99/mo vs $169/mo), so the better value depends on which treatment you need.

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Brightmeds is a Florida-based telehealth storefront selling flat-priced compounded GLP-1s alongside TRT, sermorelin, NAD+ and glutathione, with care from third-party medical groups.

Visit Brightmeds
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Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

Visit Enhance.MD

Score Breakdown

DimensionBrightmedsEnhance.MD
Overall Score66.5/10066.9/100 ✓
Trust & Safety30%60/10076/100 ✓
Value25%70/100 ✓60/100
Experience20%72/100 ✓68/100
Product Range15%72/100 ✓60/100
Reputation10%58/10065/100 ✓

At a Glance

Founded20232019
HeadquartersBrandon, FLSan Diego, CA
Publicly tradedNoNo
Treatment categories42
Treatments listed75
Starting price$99/mo$169/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryBrightmedsEnhance.MD
Weight Loss / GLP-1$99–$399
Compounded Semaglutide
$169
Microdose Tirzepatide
Longevity & Peptides$99–$199
Glutathione
$169
NAD+ Therapy

Brightmeds

+Terms name its prescribing medical groups (M & D Integrations, TelegraMD) and dispensing pharmacies (Southend, Red Rock)
+Flat GLP-1 pricing at every dose, with visits and shipping bundled and a refund if not approved
+TRT program includes lab testing for the first year plus quarterly check-ins
−Prices for the same drug differ by landing page (semaglutide $129/mo on promo pages vs $289–399/mo elsewhere)
−Longevity and TRT prices are not shown on the main product catalog and are only visible inside individual funnels
−Short operating history; LLC formed December 2023
Read the full Brightmeds review →

Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

Brightmeds vs Enhance.MD — FAQ

Is Brightmeds better than Enhance.MD?

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Enhance.MD scores higher overall in our independent evaluation (66.9/100 vs 66.5/100), leading on trust & safety, reputation. Brightmeds comes out ahead on value, experience, product range. Brightmeds has the lower entry price (from $99/mo vs $169/mo), so the better value depends on which treatment you need.

Is Brightmeds or Enhance.MD cheaper?

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Brightmeds has the lower starting price (from $99/mo vs $169/mo for Enhance.MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Brightmeds and Enhance.MD both offer?

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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides. Brightmeds covers 4 treatment categories total and Enhance.MD covers 2.

Still deciding?

Brightmeds alternativesEnhance.MD alternativesTake the Match Quiz