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Defy Medical vs Fem Excel: Which Is Better?

Head-to-head comparison of Defy Medical and Fem Excel based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 63.9/100), leading on trust & safety, experience, product range, reputation. Fem Excel has the lower entry price (from $108/mo vs $150/mo), so the better value depends on which treatment you need.

72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
64

Women's bioidentical hormone therapy arm of Excel Medical (sister brand of Male Excel), pairing a $99/mo membership with separately billed compounded estradiol, progesterone, testosterone and thyroid.

Visit Fem Excel

Score Breakdown

DimensionDefy MedicalFem Excel
Overall Score71.9/100 ✓63.9/100
Trust & Safety30%72/100 ✓66/100
Value25%60/10060/100
Experience20%78/100 ✓72/100
Product Range15%78/100 ✓55/100
Reputation10%80/100 ✓64/100

At a Glance

Founded2011—
HeadquartersTampa, FLCharlotte, NC
Publicly tradedNoNo
Treatment categories32
Treatments listed45
Starting price$150/mo$108/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalFem Excel
Hormone Therapy$150–$250
Women's Bioidentical HRT
$114–$149
Testosterone for Women (compounded)

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

Fem Excel

+Medication prices are published per drug ($50/mo core hormones, testosterone from $15/mo, metformin from $24/mo)
+Full women's hormone menu including testosterone and thyroid, plus metformin and spironolactone for PCOS
+Consistent patient sentiment (4.5/5 Trustpilot on about 820 reviews) and the company answers 95% of negative reviews
−Mandatory $99/mo membership stacks on top of medication, so a two-hormone regimen is about $199/mo before shipping
−Medications are billed every two months, doubling each charge
−Unavailable in AK, AR, CT, HI, ID, LA, MS, NH and RI
Read the full Fem Excel review →

Defy Medical vs Fem Excel — FAQ

Is Defy Medical better than Fem Excel?

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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 63.9/100), leading on trust & safety, experience, product range, reputation. Fem Excel has the lower entry price (from $108/mo vs $150/mo), so the better value depends on which treatment you need.

Is Defy Medical or Fem Excel cheaper?

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Fem Excel has the lower starting price (from $108/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and Fem Excel both offer?

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Both platforms treat Hormone Therapy. Defy Medical covers 3 treatment categories total and Fem Excel covers 2.

Still deciding?

Defy Medical alternativesFem Excel alternativesTake the Match Quiz