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Defy Medical vs Healthspan: Which Is Better?

Head-to-head comparison of Defy Medical and Healthspan based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 71.3/100), leading on experience, product range, reputation. Healthspan comes out ahead on value. Healthspan has the lower entry price (from $25/mo vs $150/mo), so the better value depends on which treatment you need.

72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
71

Healthspan is a Santa Monica-based longevity clinic built around clinician-guided rapamycin protocols, with add-on hormone, metabolic and brand-name GLP-1 care under a $99/mo membership.

Visit Healthspan

Score Breakdown

DimensionDefy MedicalHealthspan
Overall Score71.9/100 ✓71.3/100
Trust & Safety30%72/10072/100
Value25%60/10068/100 ✓
Experience20%78/100 ✓72/100
Product Range15%78/100 ✓74/100
Reputation10%80/100 ✓72/100

At a Glance

Founded20112019
HeadquartersTampa, FLSanta Monica, CA
Publicly tradedNoNo
Treatment categories37
Treatments listed414
Starting price$150/mo$25/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalHealthspan
Hormone Therapy$150–$250
Women's Bioidentical HRT
$64
Testosterone Topical Cream
Weight Loss / GLP-1$150–$250
GLP-1 Weight Loss (Semaglutide/Tirzepatide)
$248–$398
Wegovy Pill with Ongoing Care

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

Healthspan

+Deepest rapamycin-centered longevity formulary we track: oral and topical rapamycin, SGLT2 inhibitors, metformin, acarbose, LDN and methylene blue
+Low entry pricing for core longevity drugs (rapamycin from $64/mo, metformin $27, acarbose $25), shown on the homepage
+Strong patient sentiment: 4.8/5 across ~402 Trustpilot reviews, with a founder who responds personally to negative reviews
−Brand-name GLP-1s require the $99+/mo membership on top of the medication cost ($299/mo Zepbound, $149/mo Wegovy pill)
−Longevity uses of rapamycin, SGLT2 inhibitors and metformin are off-label, and headline claims (e.g., an 8-year average biological-age reduction) are self-reported
−Dispensing pharmacy and medical group are not named on the public site
Read the full Healthspan review →

Defy Medical vs Healthspan — FAQ

Is Defy Medical better than Healthspan?

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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 71.3/100), leading on experience, product range, reputation. Healthspan comes out ahead on value. Healthspan has the lower entry price (from $25/mo vs $150/mo), so the better value depends on which treatment you need.

Is Defy Medical or Healthspan cheaper?

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Healthspan has the lower starting price (from $25/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and Healthspan both offer?

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Both platforms treat Hormone Therapy, Weight Loss / GLP-1. Defy Medical covers 3 treatment categories total and Healthspan covers 7.

Still deciding?

Defy Medical alternativesHealthspan alternativesTake the Match Quiz