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Defy Medical vs IVY RX: Which Is Better?

Head-to-head comparison of Defy Medical and IVY RX based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 64/100), leading on trust & safety, experience, product range, reputation. IVY RX comes out ahead on value. IVY RX has the lower entry price (from $90/mo vs $150/mo), so the better value depends on which treatment you need.

72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
64
IVY RX
Fair

IVY RX is a Miami-based cash-pay telehealth platform, founded by a pharmacist in 2023, selling compounded GLP-1 injections, microdoses and oral melts alongside NAD+, sermorelin, glutathione and B12 injections.

Visit IVY RX

Score Breakdown

DimensionDefy MedicalIVY RX
Overall Score71.9/100 ✓64/100
Trust & Safety30%72/100 ✓55/100
Value25%60/10068/100 ✓
Experience20%78/100 ✓70/100
Product Range15%78/100 ✓70/100
Reputation10%80/100 ✓60/100

At a Glance

Founded20112023
HeadquartersTampa, FLMiami, FL
Publicly tradedNoNo
Treatment categories32
Treatments listed410
Starting price$150/mo$90/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalIVY RX
Weight Loss / GLP-1$150–$250
GLP-1 Weight Loss (Semaglutide/Tirzepatide)
$90
Metformin

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

IVY RX

+Large, positive Trustpilot base (4.7/5 across 7,300+ reviews) and replies to 91% of negative reviews
+Multiple GLP-1 formats (weekly injection, microdose, daily oral melts) plus branded Ozempic and Mounjaro
+Broad longevity menu (NAD+, sermorelin, glutathione, MIC-B12) with prices published before intake
−No lab work required before GLP-1 prescribing
−Markets '503B/USP <797>' sourcing, but a reviewer's order shipped from a 503A pharmacy
−BBB rating of C+ with 18 complaints over refill delays and billing after cancellation; refund policy is restrictive
Read the full IVY RX review →

Defy Medical vs IVY RX — FAQ

Is Defy Medical better than IVY RX?

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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 64/100), leading on trust & safety, experience, product range, reputation. IVY RX comes out ahead on value. IVY RX has the lower entry price (from $90/mo vs $150/mo), so the better value depends on which treatment you need.

Is Defy Medical or IVY RX cheaper?

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IVY RX has the lower starting price (from $90/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and IVY RX both offer?

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Both platforms treat Weight Loss / GLP-1. Defy Medical covers 3 treatment categories total and IVY RX covers 2.

Still deciding?

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