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Defy Medical vs JRNYS: Which Is Better?

Head-to-head comparison of Defy Medical and JRNYS based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 62.8/100), leading on trust & safety, value, experience, product range, reputation. JRNYS has the lower entry price (from $89/mo vs $150/mo), so the better value depends on which treatment you need.

72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
63
JRNYS
Fair

JRNYS is an Austin-based, physician-founded weight-loss membership. It prescribes branded and compounded GLP-1s, sexual-health drugs and NAD+/glutathione, with tiered coaching memberships from $89 to $169/mo.

Visit JRNYS

Score Breakdown

DimensionDefy MedicalJRNYS
Overall Score71.9/100 ✓62.8/100
Trust & Safety30%72/100 ✓64/100
Value25%60/100 ✓55/100
Experience20%78/100 ✓66/100
Product Range15%78/100 ✓72/100
Reputation10%80/100 ✓58/100

At a Glance

Founded20112022
HeadquartersTampa, FLAustin, TX
Publicly tradedNoNo
Treatment categories33
Treatments listed47
Starting price$150/mo$89/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalJRNYS
Weight Loss / GLP-1$150–$250
GLP-1 Weight Loss (Semaglutide/Tirzepatide)
$89–$169
Weight Loss Membership (Basic / Tier I / Tier II)
Sexual Health——

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

JRNYS

+Named physician founder and CMO (Dr. Henry Legere, Columbia MD, Harvard fellowship)
+Supports both insurance-covered branded GLP-1s and cash-pay compounded semaglutide/tirzepatide
+Coaching built into membership, with one-on-one sessions every six weeks (Tier I) or weekly (Tier II)
−Compounded GLP-1 prices are not published and are only quoted after the provider consult
−The $89–169/mo membership is billed on top of medication, pushing all-in cash-pay cost above flat-fee competitors
−BBB rating of C with 20 complaints closed in the past three years
Read the full JRNYS review →

Defy Medical vs JRNYS — FAQ

Is Defy Medical better than JRNYS?

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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 62.8/100), leading on trust & safety, value, experience, product range, reputation. JRNYS has the lower entry price (from $89/mo vs $150/mo), so the better value depends on which treatment you need.

Is Defy Medical or JRNYS cheaper?

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JRNYS has the lower starting price (from $89/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and JRNYS both offer?

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Both platforms treat Weight Loss / GLP-1, Sexual Health. Defy Medical covers 3 treatment categories total and JRNYS covers 3.

Still deciding?

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